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Please answer questions in short answer or paragraphs. Write enough to provide clarity and answer each...

Please answer questions in short answer or paragraphs. Write enough to provide clarity and answer each questions thoroughly in the sake of brevity. Answers should be type-written and submitted through Canvas or turned in at the beginning of class on the specified date.

Malaria parasite development in the mosquito host is complex involving many different stages and developmental roadblocks that must be overcome for transmission. What physical barriers must parasites invade in the mosquito host to complete development? What stages of the parasite are involved? At what point in their life cycle are parasite numbers the lowest?

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Answer #1

The initial step in the entry of malarial parasite into mosquito is the entry into the salivary gland of the arthopod vector.

In the mosquito, the sexual stage of parasite takes place. This sexual phase is called sporogony. When female anopheles draws blood meal from an infected individual, the male and female gametocytes enter into the gut of mosquito.

These gametes fuse to zygotes, which develop into actively moving ookinetes that develop into oocyst on the gut wall.

Development of each oocyst produces thousands of haploid forms called sporozoites. After the sporozonic phase, oocyst bursts and releases sporozoites into body cavity of mosquito which travel to salivary glands and infects another human when the mosquito sucks blood from that human.

Parasite number are lower during the oocyst stage and ththen expand quickly when each oocyst releases thousands of sporozoites.

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