Part Ill. Reactions and Mechanisms. (Total 48 points) For the following reactions, provide the products. Indicate...
provide mechanisms to explain the following reactions. Show all key intermediates and indicate electron flow using arrows. оСнз С. CH3ОН, н* Et OH H2SO4 b. Et heat
9. Provide the major products and mechanisms for the following reactions. (16 points) OH 1) NaH 2) CH,CH! CH2CH3
5. Provide reasonable step-by-step mechanisms for the following reactions. Use arrows to indicate the movement of electrons. cat. NaOCH CH,OH (solvent) cat. NaOH, НО (solvent)
was to indicate the 3. Provide reasonable step-by-sten mechanisms for the following reactions. Use arrows to india movement of electrons. OH Ho catalytic HO cat. NaOCHE CH,OH (solvent) OH cat. NaOH, HO (solvent)
5. Provide reasonable step-by-step mechanisms for the following reactions. Use arrows to indicate the movement of electrons. cat. NaOCH CH, OH (solvent) OCH cat. NaOH, H20 (solvent)
5. Provide reasonable step-by-step mechanisms for the following reactions. Use arrows to indicate the movement of electrons. cat. NaOCH. CH,OH (solvent) de e o sp. Lyra cat. NaOH, HO (solvent)
6. Provide reasonable step-by-step mechanisms for the following reactions. Use arrows to indicate the movement of electrons. catalytic CH.CH (solvent) cat. NaOH, H-O (solvent) 1 equiv HBE CH2Cl2 (solvent) 1 equiv NaOCH 00..... + CH,OH . NaBr Br CH OH (solvent)
3. Provide step-by-step mechanisms to account for the product of each of the following reactions. Show the structure of each of the intermediates and use curved arrows to indicate electron flow in each of these steps. A. cat. H30 H20 OH B. H20
In each of the following nucleophilic addition reactions (i) using arrows provide a mechanistic explanation of the course of the reaction (show intermediates); (ii) write the product of the reaction. (32 points) a. Show mechanism of acetal formation through hemiacetal reacting acetone with (1R,2S)- cyclopentan-1,2-diol under acidic catalysis. The actal formation reaction from hemiacetal is intramolecular reaction. (6 points = 3 points for hemiacetal + 3 points for acetal)
2. Draw the mechanism for the following reactions, including all arrows, intermediates, products, and formal charges. (6 points)