Question

Genetics Help

The table presents the effects of different media on the growth response of auxotrophic tryptophan mutations in Salmonella typhimurium (+ = growth, - = no growth) Based on these results, you can conclude that the trp 3 strain has a mutation in the gene that encodes the enzyme that converts... Select one: a. indole to anthranilic acid b. IGP to anthranilic acid c. indole to IGP d. anthranilic acid to indole e. IGP to indole

Answer 1

The correct answer is option e. IGP to indole.

From the above table, we can conclude the correct pathway would be

Anthranilic acid $\rightarrow$ IGP $\rightarrow$ Indole $\rightarrow$ Tryptophan

Trp8 mutant has a mutation in the gene encodes for enzyme for the production of Anthranillic acid from minimal medium\

Trp2 mutant has a mutation in the gene encodes for enzyme for the conversion of Anthranillic acid to IGP

Trp3 mutant has a mutation in the gene encodes for enzyme for the conversion of IGP to Indole

Trp1 mutant has a mutation in the gene encodes for enzyme for the conversion of IGP to tryptophan.

By this we can conclude tha trp3 mutant is an auxotrophic mutant for indole. i.e if Indole is supplied to the medium trp3 can grow.