**SYNTHESIS QUESTION: HELP NEEDED!**
Show the steps for the reagents for the following molecule (Lexapro). I've figured out the synthesis for the molecule on the right(in materials), but I can't figure out how to create the other benzene-based molecule with the nitrile attached that I need to finish the whole molecule. I think that benzaldehyde needs to be synthesized and then converted to an ester and then attached, but I can't figure out how starting from benzene.
Please show the steps of the reaction and label the reagents; also indicate the name of the reaction/reaction type(ex. F Crafts Acylations, hydrohalogenation, EAS, etc). The only Carbon sources you can use (other than the part of the molecule I synthesized with the fluorine on it) are benzene, alkanes with 3 or fewer carbons, CO2, CO, and CN. Thanks for your help!!
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**SYNTHESIS QUESTION: HELP NEEDED!**
Show the steps for the reagents for the following molecule
(Lexapro). I've...
Proposed Synthesis Show the structure of your target molecule as well as synthetic schemes illustrating the two st...
Proposed Synthesis Show the structure of your target molecule as well as synthetic schemes illustrating the two steps required for preparing it from "allowed" starting materials. For each synthetic step indicate the source of the experimental procedure you will follow-sources can either be literature references or simply the course pack itself. (See the example below for the format to be followed) ~Example Target Molecule: NO2 Cl Step 1: OH Reference: Tetrahedron, 1990, 46, 2975 HNO3 Step 2 o H2SO4 NO2...
Can you help me identify reagent (i), Compound 8 and Compound 12 in the reaction scheme?...
Can you help me identify reagent (i), Compound 8 and
Compound 12 in the reaction scheme?
You have laboratory data on all the compounds in the
synthesis, however the amount of data available to you varies. Some
have the entirety of the spectral data, others have as little as
the elemental analysis. Use the laboratory data to help you
discover which reaction has been performed.
The lab data for Compound 8 and 12 is as
follows:
You can use any...
Synthesis of crude product. 1. Combine reagents (following either step A or B, depending on the...
Synthesis of crude product.
1. Combine reagents (following either step A or B, depending on the
benzaldehyde assigned to
you). It is best not to use a brand-new conical vial right out
of the package, as the surface is not rough enough to help induce
precipitation.
A. In a 5-mL conical vial, combine 0.15 g of 3-nitrobenzaldehyde
(151.121 g/mol), 0.12 mL
of acetophenone (120.151 g/mol; d = 1.03 g/mL), and 0.80 mL of
95% ethanol.
OR
B. Pipette 0.13 mL...
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules...
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry....
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
Proposed Synthesis Show the structure of your target molecule as well as synthetic schemes illustrating the two steps required for preparing it from "allowed" starting materials. For each synthetic step indicate the source of the experimental procedure you will follow-sources can either be literature references or simply the course pack itself. (See the example below for the format to be followed) ~Example Target Molecule: NO2 Cl Step 1: OH Reference: Tetrahedron, 1990, 46, 2975 HNO3 Step 2 o H2SO4 NO2...
Can you help me identify reagent (i), Compound 8 and
Compound 12 in the reaction scheme?
You have laboratory data on all the compounds in the
synthesis, however the amount of data available to you varies. Some
have the entirety of the spectral data, others have as little as
the elemental analysis. Use the laboratory data to help you
discover which reaction has been performed.
The lab data for Compound 8 and 12 is as
follows:
You can use any...
Synthesis of crude product.
1. Combine reagents (following either step A or B, depending on the
benzaldehyde assigned to
you). It is best not to use a brand-new conical vial right out
of the package, as the surface is not rough enough to help induce
precipitation.
A. In a 5-mL conical vial, combine 0.15 g of 3-nitrobenzaldehyde
(151.121 g/mol), 0.12 mL
of acetophenone (120.151 g/mol; d = 1.03 g/mL), and 0.80 mL of
95% ethanol.
OR
B. Pipette 0.13 mL...
Page 1 Synthesis using Carbonyl O-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the organic starting material (what you have to work backwards toward) depends...
Synthesis using Carbonyla-Substitution Chemistry Preamble This experiment involves the synthesis of target molecules using a-substitution chemistry. You are assigned two target molecules, one of which is best synthesized by an alkylation approach, while the other is best synthesized by an addition or condensation approach. My two target molecules are number 2 and number 12 in the last page. You must do the following: 1. Perform a retrosynthetic analysis on the two target molecules assigned to you. In each case the...
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