The following Aldol Condensation produces a mixture of SIX -alpha, beta-unsaturated carbonyl products. DRAW the structure...
5) Draw the Structure of ALL the alpha/beta unsaturated carbon obtained as the dehydration products from the following aldol cond ůco + nsaturated carbonyl products that would be he following aldol condensation: NaOEt 6) The Aldol Condensation below provides only ONE PRODUCT. Provide the structure of the Aldol Dehydration Product and a Full Mechanism to account for its formation. C. –
Preparation of and alpha, beta-unsaturated ketone via Michael and Aldol Condensation: 6-ethoxycarbonyl-3,5-diphenyl-2-cyclohexanone.Draw a mechanism for each of the three steps in the preparation of 6-ethoxycarbonyl-3,5-diphenyl-2-cyclohexenone. You may assume that NaOH functions as a base andethanol serves as a proton source
Rheosmin is a saturated ketone obtained from an
alpha,beta-unsaturated ketone (a crossed aldol condensation
product) which is capable of undergoing hydrogenation to yield a
saturated ketone (Rheosmin). Using this technique, identify the
reagents needed to prepare Rheosmin via crossed aldol reaction.
Rheosmin 4-(4-hydroxyphenyl)butan-2-one
This reaction is an example of conjugate addition of a nucleophile to an alpha, beta-unsaturated carbonyl. Draw the two resonance structures of the enolate anion intermediate for this reaction.
3. Draw all the aldol addition products that are formed when a
mixture of acetaldehyde and pentanal is treated with aqueous sodium
hydroxide.
4. A reaction, such as described in question 3, which produces a
mixture of products is generally not useful for organic synthesis.
Suggest a change in the reaction starting materials for question 3
that would produce a single, similar product.
5. Draw a generic mechanism for aldol condensation.
6. The last step for an aldol condensation involves...
4. Draw all of the possible Aldol products (B-hydroxycarbonyl) for the following reaction below. Condensation products are not necessary. (3 points) NaOH Aldol Products
The Stork reaction is a condensation reaction between an enamine donor and an a,B-unsaturated carbonyl acceptor. The overall reaction consists of a three-step sequence of 1. formation of an enamine from a ketone, 2. Michael addition to an a,B-unsaturated carbonyl compound, and 3. hydrolysis of the enamine in dilute acid to regenerate the ketone. Consider the Stork reaction between acetophenone and 3-buten-2-one. 1 Draw the structure of the product of the enamine formed between acetophenone and dimethylamine. N - O...
4. Draw all of the possible Aldol products (B-hydroxycarbonyl) for the following reaction below. Condensation products are not necessary. (3 points) NaOH Aldol Products .Ph Me H2O Ph Ме
Draw the starting materials for the compound given below via directed aldol condensation reaction. Show the resonance structure for the following, α,β-unsaturated ketone. 1. Propose reagents or products as needed (you will need sets of reagents for arrows pointing left and 1 product for the right facing arrow). 2. H3C-SH HO
Draw the structures of the aldol addition and condensation products of pentanal. Draw only one final condensation product.