Question

A 27 year old woman is given intravenous penicillin to treat infective endocarditis. Within minutes of...

A 27 year old woman is given intravenous penicillin to treat infective endocarditis. Within minutes of starting this therapy, she begins to have severe difficulty breathing with respiratory stridor and tachypnea. She suddenly develops an erythematous rash over most of her body. Her symptoms are most likely to be produced by which of the following chemical mediators:

A. Interleukin 1

B. IgG

C. MAC

D. Histamine

E. Perforin

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Answer #1

Option - D Her symptoms are most likely to be produced by Histamine. Histamine is produced as immediate response to a foreign antigen by mast and basophils present in near by connective tissues.

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