Question

Part A What is the main technical difference in how DNA is modified that differs between these approaches? Drag the terms on the left to the appropriate blanks on the right to complete the sentences. Not all terms will be used. Reset Help unforeseen sequences DNA modification by gene targeting relies on to remove sequences reverse transcription and replace them with the desired sequences nucleases Gene editing, by contrast, utilizes o break DNA in , which allows exogenous genes to be either removed, corrected, or replaced. manner endogenous homologous recombination guide RNA Submit Request Answer

Answer 1

- DNA modification by gene targeting relies on homologous recombination to remove endogenous sequences and replace them with the desired exogenous sequences.

- Gene editing by contrast utilizes nucleases to break DNA in a sequence specific manner ,which allows gene to be either removed, corrected or replaced.