Question

Reactive species production and inflammation are very much intertwined. Which of the following is LEAST likely...

Reactive species production and inflammation are very much intertwined. Which of the following is LEAST likely to be a key player in the inflammation-mediated cancer pathogenesis:

a) NF-kB

b) eNOS

c) TNF-a

d) iNOS

e) COX-2

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Answer #1

Option 2

Endothelial Nitric oxide synthase (eNOS) is an inducible enzyme in the endothelial cells and it has anti inflammatory role

Where as NF-kb, TNF -alpha, iNOS, COX-2 are all involved in the either initiation or progression of inflammation

Hope this helps...thank you!!!

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