4.2 Give a detailed mechanism and show the products of the following reactions: OF CH3 C...
Tell whether each of the following reactions are likely to be Sn1, Sn2, E1, E1CB, or E2 and provide a mechanism for the transformation in part a. Tell whether each of the following reactions is likely to be Sn1, Sn2, E1, E1cB, or E2: кон Ethanol Br нсон H20
V. What are the major products of the following reactions (if any), and the plausible mechanism (SN1, SN2, E1, E2)? Br NaSCH acetone KO'Bu THF, A NaNH2
1. Assign the correct mechanism for the process that will predominantly take place in the reactions A-F shown. Your three choices are: SN2 or E2 or (SN1+E1) Hint: As practice for the exam, make sure that you can CONFIDENTLY draw the structures of all the products formed in these reactions by the predominant mechanisms that you select! a) A: SN2; B: E2; C: SN1+E1; D: E2; E: SN2; F: SN1+E1 b) A: E2; B: SN2; C: E2; D: SN2; E:...
8. complete the following reactions. mention the type of mechanism (SN1,SN2, E1, or E2) that each follows 8. Complete the following reactions. Mention the type of mechanism (SNI, SN2, E1 or E2) that each reaction follows. (4) (CHy)COH 100°C Br a) Cl Xiocn, NaOCH3 Heat CH3 b) Cl CH3ONa CH3OH,100°C CH3
7) Give the mechanism including the transition state. сн.ct çı SN2 НН 8) Give the mechanism. CH1 보 SN1 CHCH,CH-C CH. но H Br 9) Give the mechanism of the reaction shown below. CH CI E1 CH,OH 10) When 1-bromo-2,2-dimethylcyclopentane is heated in ethanol, one of the products which results is shown below. Provide a detailed, stepwise mechanism for the production of this compound, and give the name of the mechanism by which it is produced. CH3 CH3
elimination/substitution reactions TsO. он 1. TsCl, pyr 2. NaN Ph н. CH3 NaOH Н,с E2 Only CH2CH он. Br LDA но Он HSO Нeat Ring expansion H2SO Нeat он 5. Identify each position where an SN1, or SN2 reaction is likely to occur. If there is the potential for both, state SN1 or SN2 TsO. Br NH2 NO
20. Arrange the following molecules based on their reactivity for SN1 mechanism (the most reactive to the least reactive) [4pts] Br Br CH3Br Br 21. Considering the SN1, SN2, E1, and E2 mechanisms, the energy diagram shown below corresponds to [4Pts] a. only the SN1 mechanism b. only the E1 mechanism c. both the SN2 and E2 mechanisms d. only the SN2 mechanism. e. only the E2 mechanism f. both the SN1 and El mechanisms energy rxn coordinate 22. If...
10). (18 pts) Predict the structures of the products from each of the following S2 reactions. If no reaction is expected, write "No Rxn" Hас. H,с-о° Br A). н,с- он сH H,с. KBr сH, В). acetone он NaN С). ethanol Br CH3 кCN D). H,с. Br DMSO сн, SH но E) CH3 ethanol "сH,
2. Draw the mechanism of the following reactions using arrows to show the flow of electrons а. Br 2 eq. NaNH2 N Br b. p-TSOH is a strong acid like H2SO OH p-TSOH Гон Cн.Cl A d. NaBH Но D но. е. Н,о* он но н
3. Shown below are a series of reactions. Predict the major product for each of them. Remember, you will need to first decide whether the reaction occurs by an SN2, SN1, E2, or E1 before you can determine what the product will be. Label each as SN2, SN1, E2, or E1. Hint: First decide whether S2/E2 or S1/E1 is favored, and then decide whether the reaction pathway goes by a substitution or elimination reaction. SN2 / SN1 E2/E1 Na DMSO,rt...