What are MAC's and how do they kill a pathogenic threat to the body?
What are MAC's and how do they kill a pathogenic threat to the body?
Homework Answers
Ans: Membrane attack is an important mechanism in many of the mammalian immune defence system against pathogens and infected host cells. For eg: In human protection against bacteria depends on the activation of the terminal pathway of the complement system. The activation of this pathway leads to the formation of Membrane Attack Complex which forms a pore in the membrane leading to the lysis of the targeted cells.
MAC is typically formed on the surface of the pathogens cell membrane. It allows entrance and exit of ions, water and other small molecules to move freely in and out of the cell and ultimately results in the cell death due to change in this osmotic flux as well as showing impacts on tissue homeostasis of self-cells. However it should be noted that MAC can rupture cell membrane of bacteria as well as of host cells of not properly controlled.
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What are MAC's and how do they kill a pathogenic threat to the
body?
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the human body responds in many ways to the invasion of
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the human body responds in many ways to the invasion of
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