Lysosome = Digestive bags of the cell = Suicidal bags of the
cell
They contain several hydrolytic enzymes responsible for the
breakdown of several biomolecules.
Lysosomal targeted proteins are synthesized on ribosomes
attached to the ER (RER).
The nascent peptide is released into the ER lumen for proper
folding and post-translational modifications.
The nascent peptide is then transported to the cis-Golgi where it
further undergoes post-translational modifications.
Proteins destined for a lysosome are tagged with a
mannose-6-phosphate label.
The functional proteins and packed into vesicles and fuse with the
lysosomes.
describe how an enzyme that is destined for the lysosome gets synthesized and transported
Newly synthesized proteins destined for the lysosome bind a specific receptor in the -------- and are released from their receptor in the -------.
What is a lysosome? What is its function? b) How are hydrolytic enzymes selected and transported (trafficked) into a lysosome? c) What is a lysosomal storage disease? d) Name ONE lysosomal storage disease and describe the genetic defect that leads to the disease.
Describe the main mechanisms by which newly synthesized proteins are transported from the cytosol to mitochondria and outline the importance of signal sequences and protein processing in the localization of proteins within the different compartments of the mitochondrion.
2.222 points Saved QUESTION 3 Approximately how many protons must be transported into each lysosome to lower the pH to 5.0 from 8.0? Diameter of lysosome is 03. 0.6 x 10 m 300-900 0 1500-3000 85-680 Not enough information was given QUESTION 4 2.222 points Save Answer What concentration of HBr will have a pH of 4.07 1x10.4 1x10.8 1x10-2 6x10-1
When looking for a specific enzyme in various compartments of a cell (nucleus, mitochondria, lysosome, microsome, and cytosol), why would the DNA concentration be measured? Please give a detailed explanation.
Describe the Na+-glucose transporter. Describe how glucose is transported from the intestinal lumen to the extracellular fluid in the gut lining.
Neurotransmitters are synthesized in the cytoplasm of cells and transported to cell vesicles for storage. Neurotransmitters use an antiport exchanger protein that is proton dependent. Based on the information above, it can be concluded that Hint: This transport is an example of secondary active transport. Select one: a. the pH in the interior of the vesicle is higher than the cytoplasm. b. the pH in the interior of the vesicle is lower than the cytoplasm.
Describe how carbon dioxide is taken into blood at the tissue capillaries, transported in the blood, and discharged at the lung capillaries. Be complete.
1. Describe how proteins are targeted and synthesized in the ER. 2. Describe nuclear pore transport. Why a pore and not a simple membrane translocator? 3. Describe how exocytose and endocytose vesicle targeting mechanisms.
1. Describe the processes by which fatty acids are transported in the blood, activated and transported into the matrix of the mitochondria for breakdown to obtain energy. (Specifically, determine the role of carnitine palmitoyl transferase in the oxidation of fatty acids.) 2. Explain the processes by which fatty acids are released from triacylglycerol stored in adipose tissue. 3. Outline the β-oxidation pathway by which fatty acids are metabolized to acetyl-CoA and explain how this leads to the production of large...