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Newly synthesized proteins destined for the lysosome bind a specific receptor in the -------- and are...

Newly synthesized proteins destined for the lysosome bind a specific receptor in the -------- and are released from their receptor in the -------.

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ANSWER :-

  1. There are certain receptors are usually associated with the matured Golgi apparatus also called as the trans-splicing apparatus. This is then followed by formation of the secretory vesicles which migrates to the late-endosomes.
  2. The golgi apparatus plays a vital role in sorting of the proteins to their destined position. More specifically, the proteins that are targetted to the Lysosome are synthesized in the rough Endoplasmic Reticulum followed by transport to the Golgi.
  3. The golgi network further leads to formation of specific vesicles also called as transport vesicles which fuses with the late-endosomes leading to the formation of lysosomes after maturation.
  4. So, newly synthesized proteins destined for the lysosomes bind a specific receptor in the trans-Golgi apparatus and are released from their receptor in the transport vesicles.

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