The ability of a single signal molecule to bind to a receptor and trigger several signal...
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The ability of a single signal molecule to bind to a receptor and trigger several signal transduction pathways simultaneously:
a. Is common to all plasma membrane receptor proteins
b. Does not occur in animals
c. Is a key feature of the receptor tyrosine-kinase system
d. Uses a diacylglycerol-mediated pathway
Homework Answers
The signal transduction pathways involve binding of a signal molecule to the cell surface receptor and it causes the intracellular changes by phosphorylation. In animals, there are several physiological processes that depend on signal transduction processes. The plasma membrane phospholipids like phosphatidylinositol are phospholrylated and cleaved into DAG (diacyl glycerol) and IP3 (inositol triphosphate) by the enzyme phospholipase C. The DAG remain in plasma membrane and IP3 diffuses into cytoplasm to trigger signal cascade by releasing intracellular calcium from endoplasmic reticulum. The receptor tyrosine kinases (RTK) are cell surface receptors of various proteins like cytokines and hormones etc. The are involved in siganl transduction by binding with an appropriate ligand undergo dimerization of receptor. Phosphorylation and activation of the proteins on receptor binding lead to the initiation of signal transduction pathways and RTK receptors phosphorylate multiple tyrosine residues and can activate multiple signal transduction pathways. Therefore, the option c is correct.
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