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Explain how the adaptive immune response is able to generate the diversity of antigen receptors necessary...

  1. Explain how the adaptive immune response is able to generate the diversity of antigen receptors necessary to recognize the multitude of foreign antigens.
  2. Explain how clonal selection contributes to the development and expansion of antigen specific lymphocytes that do not respond to self.
  3. Distinguish cytokines and chemokines and their roles in the immune response
  4. What are the 3 roles of antibody in the immune response
  5. What are the two types of T cells that contribute to cellular immunity?
  6. What are the roles of the distinct classes of CD4 T cells in the immune response
  7. What are the two signals needed to activate both T and B cells in the adaptive immune response
  8. How is the recognition of foreign antigens different for B and T cells? What do the antigen receptors bind to?
  9. How do transcription factors recognize their specific target genes? Give examples of protein domains that contribute to DNA recognition by transcription factors.
  10. Distinguish enhancers and promotors.
  11. Diagram the cell cycle including the restriction points and know what controls movement of the cells through those restriction points
  12. Distinguish oncogenes, protooncogenes, tumor suppressors caretakers
  13. What are environmentally induced cancers
  14. Discuss the stages in tumor development
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