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Is it possible to use Thin Layer Chromatography (TLC) to analyze a distillation sample. For instance,...

Is it possible to use Thin Layer Chromatography (TLC) to analyze a distillation sample. For instance, if I completed a Simple Distillation and wanted to find the identity of the distillate, would it be possible to do this through TLC? Please explain fully why or why not.

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Answer #1

No,since after simple distillation we can separate volatile liquid from nonvolatile liquid i.e. on the basus of difference of boiling point .But TLC is generally used separate mixture of liquid on the basis of adsorption.so distillate can be identified in the way like liquid has low boiling point or more volatile vapourised first and then high boiling liquid which take time to vapourise can be collected by condensing vapour of it after sometime.

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