What is population stratification? Explain why
stratification can confound a search for the genetic basis of
a trait in a population.
population stratification refers to the differences in allele frequencies between cases and controls due to systematic differences in ancestry rather than association of genes with disease . because if cases and controls are drawn from different ethnic backgrounds frequency will vary because of genotype frequency in the population rather than because of association with a trait
What is population stratification? Explain why stratification can confound a search for the genetic basis of...
Genetic Traits and genetic disorders are influenced in one way or another by the environment. On the other hand, the heritability of a disorder examines the variations in multifactorial traits due to genetics in a particular population and focuses on the genetic component of variations seen in a trait. Select a genetic disorder caused by a single-gene trait that is multifactorial. Explain how your chosen genetic disorder is influenced by the environment. Select two diseases—one with high heritability and one...
What is the genetic basis of sensory reception – how does genetic variation explain how we see, taste, and smell different things than other people?
1. How would a scientist would recognize genetic drift, from a current population. Explain. 2. What factors would prevent genetic drift, and explain why (Good description of factors)
Why is it impossible to understand the differences in traits between groups by measuring narrow-sense heritability of those traits within the groups? What is the difference between saying there is no genetic basis for a trait and saying that all of the phenotypic variation in a trait for a given population can be explained by variation in environment?
9-20% of the population has the genetic trait A. Of these, 70% has genetic trait B. Of the population that doesn't have trait A, 40% have trait B a) A person from the population is picked at random from the) population What is the probability that this person has trait B? b) What is the probably that, knowing the person picked has trait A b) that this person also has trait B? e) What is the probably that, knowing the...
2. Assume a population is in Hardy-Weinberg equilibrium for a given genetic autosomal trait. What proportion of individuals in the population are heterozygous for the gene if the frequency of the recessive allele is 1%.
Explain how progress in genetics can help public health professionals stratify risk on the basis of biology, as contrasted with stratification of risk on the basis of exposure to environmental variables.
Using a simple group, mother and offspring, as an example, explain how direct genetic effects and indirect genetic effects can contribute to a phenotypic trait such as offspring growth rate and can be used to estimate the heritability of a group phenotypic trait. You need to mention additive genetic variance in your answer.
In terms of genetic makeup explain why evolution applies to populations and not to individual members of the population?
1. While the traits studied in Exercise 1 were hypothetical genetic traits, what type of genetic traits do you think are important to study and predict? Give an example of a genetic trait that is carefully monitored when two parents are creating an offspring and why it would be important to monitor. 2. Describe a karyotype and explain how it is performed. 3. Would a normal karyotype mean that a person would not have any disorder or disease in their...