How do both of these mechanisms lower the concentration of p27? 1. Cdk4/cyclin D 2. Cdk2/cyclin...
How do both of these mechanisms lower the concentration of p27?
1. Cdk4/cyclin D
2. Cdk2/cyclin E
Homework Answers
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How do both of these mechanisms lower the concentration of
p27?
1. Cdk4/cyclin D
2. Cdk2/cyclin...
1. p16 acts to prevent cells from moving through the cell cycle by acting on which...
1. p16 acts to prevent cells from moving through the cell cycle by acting on which cyclin-cdk pair? A. cyclin A-cdc2 B. cyclin D-cdk4/6 C. cyclin E-cdk2 D. cyclin A-cdk2 2.Which cyclin-CDK partner below is associated with G1 before the R point? A. cyclinA-cdk2 B. cyclinE-cdk2 C. cyclinD-cdk4/6 D. cyclinB-CDC2 3.Mitogens primarily affect the expression levels of which cyclin? A. cyclin B B. cyclin E C. cyclin A D. cyclin D 4. Which of the following is true about the...
Cdhl is dephosphorylated by OA. Cyclin B OB. B. PS3 Cdc14 OC. E2F D. DNA synthesis...
Cdhl is dephosphorylated by OA. Cyclin B OB. B. PS3 Cdc14 OC. E2F D. DNA synthesis is initiated when the following complex is activated O A. Cdk4-cyclinD complex O B. Cdk6-cyclinD complex Cyclin E-Cdk2 complex OC. o D. CylinA-Cdk2 complex Which of the proteins may have disulphide bonds? Proteins destined to cytoplasm O A. Proteins destined to plasma membrane OB. Proteins destined to Nucleus O C. None of A, B and C OD. Cell surface receptor that transmit the signalling...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of the APC, which in a ubiquitin E3 ligase, in the control of the metaphase cyclin (cyclin B) and the timing of events. To look at this you start by synchronizing your cells in G1 and examining the levels of Cyclin B over time. The APC usually works on cyclin B during anaphase. RBX57 is a substrate for Cylcia...
You are a studying the progression of cells through the cell cycle. You are particularly interested...
You are a studying the progression of cells through the cell cycle. You are particularly interested in the role of the APC, which in a ubiquitin E3 ligase, in the control of the metaphase cyclin (cyclin B) and the timing of events. To look at this you start by synchronizing your cells in G1 and examining the levels of Cyclin B over time. The APC usually works on cyclin B during anaphase. RBX57 is a substrate for Cylcin B/CDK2. Given...
Identify all the false statements. 1. CDK's confer target specificity to cyclin / CDK activity. 2....
Identify all the false statements. 1. CDK's confer target specificity to cyclin / CDK activity. 2. Cyclins activate CDKs. 3. Only one cyclin is requried per cell cycle. 4. CDK's are destroyed by the ubiquitination apparatus. 5. The concentration of a CDK changes less than a cyclin during a cell cycle. 2 and 5. 1, 3 and 4. 3 only. 3 and 5. 1 and 4.
B. (2 pts) From the data, propose a simple molecular explanation for how MI575 acts to...
B. (2 pts) From the data, propose a simple molecular explanation for how MI575 acts to block the cell cycle. 28. Examine the following pathway: TGFB - TGFB-R — P15(Ink4B) — cyclin D-CDK4/6 A. (3 pts) What will happen to Rb under these circumstances? B. (3 pts) Will the cell progress through the R point? Briefly explain your answer. C. (3 pts) What will happen to Rb and the cell cycle when TGFB is removed? 29. (3 pts) Based on...
2. How do you measure the waist-to-hip ratio of a client? 1. At what concentration does...
2. How do you measure the waist-to-hip ratio of a client? 1. At what concentration does the onset of blood lactate accumulation tend to occur? (give values for both trained and untrained individuals) 2. What is the term used to describe the second point of inflection in blood lactate and at what concentration does it occur? 3. What is the normal range of lactate concentration in the blood at rest? 4. True or False: A trained athlete typically has a...
GENE EXPRESSION PROFILE A RELATIVE EXPRESSION CYCLIN D RB E2F Information for the following problem: •...
GENE EXPRESSION PROFILE A RELATIVE EXPRESSION CYCLIN D RB E2F Information for the following problem: • CYCLIN D inhibits RB • RB inhibits E2F • E2F increases mitosis 1. Is the pattern seen in gene expression profile A consistent with cancer progression? If so, explain why you have come to that conclusion 2. If consistent with cancer progression, indicate the probable gene that is mutated, and if this represents an oncogenic or tumor suppressor mutation. In your explanation, make sure...
When we evaluate investment projects, a) do we prefer higher or lower NPV? (1=higher, 2=lower) b)...
When we evaluate investment projects, a) do we prefer higher or lower NPV? (1=higher, 2=lower) b) do we prefer higher or lower IRR? (1=higher, 2=lower) c) do we prefer higher or lower payback period? (1=higher, 2=lower) d) do we prefer higher or lower modified payback period? (1=higher, 2=lower) e) do we prefer higher or lower SRR? (1=higher, 2=lower)
25) In the process known as osmosis, concentration. A) solute; lower solute D) solvent; lower solvent moves through...
25) In the process known as osmosis, concentration. A) solute; lower solute D) solvent; lower solvent moves through a semipermeable membrane into an area o B) solute; higher solute E) solvent; higher solvent C) solvent; lower solute 26) A solution that has an osmotic pressure less than that of red blood cells is called A) saturated. B) hypertonic. C) isotonic. D) hypotonic. E) unsaturated 27) A red blood cell will undergo crenation in A) water. B) 0.5% NaCl. C) 3%...
Cdhl is dephosphorylated by OA. Cyclin B OB. B. PS3 Cdc14 OC. E2F D. DNA synthesis is initiated when the following complex is activated O A. Cdk4-cyclinD complex O B. Cdk6-cyclinD complex Cyclin E-Cdk2 complex OC. o D. CylinA-Cdk2 complex Which of the proteins may have disulphide bonds? Proteins destined to cytoplasm O A. Proteins destined to plasma membrane OB. Proteins destined to Nucleus O C. None of A, B and C OD. Cell surface receptor that transmit the signalling...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of the APC, which in a ubiquitin E3 ligase, in the control of the metaphase cyclin (cyclin B) and the timing of events. To look at this you start by synchronizing your cells in G1 and examining the levels of Cyclin B over time. The APC usually works on cyclin B during anaphase. RBX57 is a substrate for Cylcia...
You are a studying the progression of cells through the cell cycle. You are particularly interested in the role of the APC, which in a ubiquitin E3 ligase, in the control of the metaphase cyclin (cyclin B) and the timing of events. To look at this you start by synchronizing your cells in G1 and examining the levels of Cyclin B over time. The APC usually works on cyclin B during anaphase. RBX57 is a substrate for Cylcin B/CDK2. Given...
B. (2 pts) From the data, propose a simple molecular explanation for how MI575 acts to block the cell cycle. 28. Examine the following pathway: TGFB - TGFB-R — P15(Ink4B) — cyclin D-CDK4/6 A. (3 pts) What will happen to Rb under these circumstances? B. (3 pts) Will the cell progress through the R point? Briefly explain your answer. C. (3 pts) What will happen to Rb and the cell cycle when TGFB is removed? 29. (3 pts) Based on...
2. How do you measure the waist-to-hip ratio of a client? 1. At what concentration does the onset of blood lactate accumulation tend to occur? (give values for both trained and untrained individuals) 2. What is the term used to describe the second point of inflection in blood lactate and at what concentration does it occur? 3. What is the normal range of lactate concentration in the blood at rest? 4. True or False: A trained athlete typically has a...
GENE EXPRESSION PROFILE A RELATIVE EXPRESSION CYCLIN D RB E2F Information for the following problem: • CYCLIN D inhibits RB • RB inhibits E2F • E2F increases mitosis 1. Is the pattern seen in gene expression profile A consistent with cancer progression? If so, explain why you have come to that conclusion 2. If consistent with cancer progression, indicate the probable gene that is mutated, and if this represents an oncogenic or tumor suppressor mutation. In your explanation, make sure...
25) In the process known as osmosis, concentration. A) solute; lower solute D) solvent; lower solvent moves through a semipermeable membrane into an area o B) solute; higher solute E) solvent; higher solvent C) solvent; lower solute 26) A solution that has an osmotic pressure less than that of red blood cells is called A) saturated. B) hypertonic. C) isotonic. D) hypotonic. E) unsaturated 27) A red blood cell will undergo crenation in A) water. B) 0.5% NaCl. C) 3%...
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