Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be...
Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes through a chromatography column of length ?=45.0 cm containing ? theoretical plates. The compounds have an adjusted relative retention, α, of 1.093 and retention factors of 6.09 and 6.66 , respectively.
Calculate the number of theoretical plates, ? , in the column of length ? . The observed resolution is 1.98 after 18 cycles.
Calculate the height of an individual plate in micrometers.
Estimate the resolution after 7 cycles.
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Two isotopic compounds are produced in the synthesis of a new
therapeutic drug, which must be...
Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be...
Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes through a chromatography column with a length L = 45.0 cm containing N theoretical plates. The unadjusted relative retention is y = 1.098. Calculate the number of theoretical plates, N. in the column of length L. The observed resolution is 1.82 after 14 cycles. plates Calculate the height of an...
Check An 5 of 26 > Two isotopic compounds are produced in the synthesis of a...
Check An 5 of 26 > Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes through a chromatography column with a length L 25.0 cm containing N theoretical plates. The unadjusted relative retention is y = 1.042 Calculate the number of theoretical plates, N, in the column of length L. The observed resolution is 1.84 after 19 cycles N-...
Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes...
Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes through a chromatography column of length
Two compounds C and D are separated on a column 34 cm long . Given the...
Two compounds C and D are separated on a column 34 cm long . Given the chromatographic data below calculate The column resolution? , the number of theoretical plates ?the height of theoretical plate and what length of column would be required to give a resolution of 1.5? Compound C retention time 18.3 width at base of peak(min) = 2.18 Compound D retention time 17.7, width at base 1.23
Consider the data below for a liquid chromatography separation of four compounds, A, B, C, and...
Consider the data below for a liquid chromatography separation of four compounds, A, B, C, and D on a 45.0 cm column. Calculate the number of theoretical plates, N, for each peak. Retention Width at the Time (min) Base (min) 5.24 0.424 Number Number 12.8 1.08 NA = II 14.2 1.12 D 24.1 1.85 Number Number NB = 10 N= What is the average number of theoretical plates, Navg, for the column? Number Navy = avg What is the plate...
Chromatograms of compounds A and B were obtained at the same flowrate with two columns of...
Chromatograms of compounds A and B were obtained at the same
flowrate with two columns of equal length. The Value of tm is 1.3
min in both cases.
Chromatograms
of compounds A and B were obtained at the same flow rate with two
columns of equal length. The value of
tm is
1.3 min in both cases.
I Column 1 Column 2 12 10 Time What is the numcrical valac of the nenn factor of pak A what isthemererkal valse...
need help with number 2 HW #3 for Chem 318 Due: April 29, 2019 1. Solute A has a K 2.5 for an extraction between water (phase 1) and chloroform (phase 2). If 100 mL of a 0.01 fraction will be extr...
need help with number 2
HW #3 for Chem 318 Due: April 29, 2019 1. Solute A has a K 2.5 for an extraction between water (phase 1) and chloroform (phase 2). If 100 mL of a 0.01 fraction will be extracted? For the same solute and, what fraction will be extracted if 5 extractions wi 80 mL chloroform each are used (instead of one 400 ml extraction)? M solution containing solute A in water is extracted one time with...
Experiment Write Up Proposal You will write up a synthesis procedure for one reaction that could...
Experiment Write Up Proposal You will write up a synthesis procedure for one reaction that could be potentially run in a face- to-face Chem 2321 lab session. Your proposal will include an introduction and procedure. The procedure will include step-by-step instructions for running the reaction (including reaction monitoring), work-up. (product isolation and purification), and analysis (characterization). You will need to include sample calculations for percent yield and provide sample spectra analysis. You must upload your proposal as a single document...
Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes through a chromatography column with a length L = 45.0 cm containing N theoretical plates. The unadjusted relative retention is y = 1.098. Calculate the number of theoretical plates, N. in the column of length L. The observed resolution is 1.82 after 14 cycles. plates Calculate the height of an...
Check An 5 of 26 > Two isotopic compounds are produced in the synthesis of a new therapeutic drug, which must be separated by repeated chromatography cycles. In each cycle, the solution containing both compounds passes through a chromatography column with a length L 25.0 cm containing N theoretical plates. The unadjusted relative retention is y = 1.042 Calculate the number of theoretical plates, N, in the column of length L. The observed resolution is 1.84 after 19 cycles N-...
Consider the data below for a liquid chromatography separation of four compounds, A, B, C, and D on a 45.0 cm column. Calculate the number of theoretical plates, N, for each peak. Retention Width at the Time (min) Base (min) 5.24 0.424 Number Number 12.8 1.08 NA = II 14.2 1.12 D 24.1 1.85 Number Number NB = 10 N= What is the average number of theoretical plates, Navg, for the column? Number Navy = avg What is the plate...
Chromatograms of compounds A and B were obtained at the same
flowrate with two columns of equal length. The Value of tm is 1.3
min in both cases.
Chromatograms
of compounds A and B were obtained at the same flow rate with two
columns of equal length. The value of
tm is
1.3 min in both cases.
I Column 1 Column 2 12 10 Time What is the numcrical valac of the nenn factor of pak A what isthemererkal valse...
need help with number 2
HW #3 for Chem 318 Due: April 29, 2019 1. Solute A has a K 2.5 for an extraction between water (phase 1) and chloroform (phase 2). If 100 mL of a 0.01 fraction will be extracted? For the same solute and, what fraction will be extracted if 5 extractions wi 80 mL chloroform each are used (instead of one 400 ml extraction)? M solution containing solute A in water is extracted one time with...
Experiment Write Up Proposal You will write up a synthesis procedure for one reaction that could be potentially run in a face- to-face Chem 2321 lab session. Your proposal will include an introduction and procedure. The procedure will include step-by-step instructions for running the reaction (including reaction monitoring), work-up. (product isolation and purification), and analysis (characterization). You will need to include sample calculations for percent yield and provide sample spectra analysis. You must upload your proposal as a single document...
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