Question

Explain the problem posed by moving replication forks of a replicon in terms of how DNA Pol III functions.

Answer 1

DNA polymerase enzyme lll is a enzyme which is primarily responsible for the replication of DNA synthesis. Replication results in the leading strand and the lagging strand.

DNA polymerase lll interacts with both the strands. The enzyme in the leading strand moves in the same direction (5'-3'). For the synthesis of lagging strand, DNA polymerase lll need to work with dna B and travel in the opposite direction. The synthesis of the lagging strand is more complex than that of leading strand. Primase enzyme is required for synthesis of a primer on the lagging strand which is essential for the synthesis of fragments. For dissociating the primase from replicating fork, DNA polymerase lll interacts with the primase.