What is the difference between a radiopharmaceutical and a radioisotope?
Radiopharmaceuticals have been defined as radioactive drugs that, when used for the purpose of diagnosis or therapy, typically elicit no physiological response from the patient. This definition is strongly supported by the Nuclear Medicine community's collective experience in administering radiopharmaceuticals: most practitioners, in their entire careers, have not observed a physiological response or an adverse reaction following administration of a radiopharmaceutical.
The design of these compounds is based solely upon physiological function of the target organ. Unlike radiographic procedures, which depend almost entirely upon tissue density differences, external imaging of radiopharmaceuticals is essentially independent of the density of the target organ. The mechanism of localization of a radiopharmaceutical in a particular target organ can be as simple as the physical trapping of particles or as sophisticated as an antigen-antibody reaction or chemisorption of an inorganic phosphate on the hydroxyapatite crystals deposited in an acute myocardial infarction.
There is a significant difference between a radioisotope (a radionuclide whose chemical form is unknown) and a radiopharmaceutical whose chemical form is usually precisely known. For example, I-123 is a radioisotope with a characteristic physical half-life. Reference to a biological half-life or an effective half-life for I-123 is meaningless since we don't know the chemical form. On the other hand, I-123 NaI is a compound with known biodistribution and clearance rates and is associated with both biological and effective half-lives.
What is the difference between a radiopharmaceutical and a radioisotope?
22) Aradioactive compound used for the diagnosis and treatment of disease is called a 23) The principal difference between x-rays and gamma rays is their 24) The usual dose used for brain imaging with F-FDG is between 25) n the U.S., a patient can be released provided the TEDE to any other individual from exposure to the released and MBq patient is not ikely to exceedmrem or mSv 26) The concentration of Mo in a Tc containing radiopharmaceutical shall not...
Please show steps, thank you If a radiopharmaceutical has an effective half life of 75 seconds and a biological half life of 6 minutes what is the physical half life in minutes? If a radiopharmaceutical has an effective half life of 190 seconds and a physical half life of 42 minutes what is the biological half life in minutes? If a radiopharmaceutical has an effective half life of 110 minutes and a physical half life of 150 minutes what is...
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Review Problem5 * The half value layer of lead is o.27cm for 1131. If a radiopharmaceutical dose is producing 125mR/hr, what will be the exposure rate if the dose is placed in a lead shield that has a thickness of 4mm? Review Problem5 * The half value layer of lead is o.27cm for 1131. If a radiopharmaceutical dose is producing 125mR/hr, what will be the exposure rate if the dose is placed in a lead shield that has a thickness...
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Show steps please If a radiopharmaceutical has an effective half life of 36 hours and a biological half life of 8 days what is the physical half life in hours?
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