Draw the structures of the hydroxyaldehyde and the α,β-unsaturated aldehyde product from the self-aldol reaction of each of the following, propanal, phenylethanal, 3-phenylpropanal and benzaldehyde.
Draw the structures of the hydroxyaldehyde and the α,β-unsaturated aldehyde product from the self-aldol reaction of...
1. Draw the reactants and dehydrated aldol product for your assigned aldehyde–ketone pair. 2. Using your assigned aldehyde–ketone pair, draw a base-catalyzed mechanism producing the dehydrated aldol product, an α,β-unsaturated ketone. Aldehyde is benzaldehyde Ketone is cyclohexanone
Draw structural formulas for the α,β-unsaturated aldehyde or
ketone and the lithium diorganocuprate (Gilman reagent) that could
be used in a synthesis of the compound shown below.
Draw a structural formula for the major organic product of the
reaction shown below.
We were unable to transcribe this imageether H2O + Culi
Post-lab questions (1) In a Michael reaction, an α carbon attacks the β carbon of an α,β-unsaturated carbonyl com pound to afford a 1,5-dicarbonyl compound. Ethyl acetoacetate has two a carbons: why does the a carbon sandwiched between the two carbonyls conduct the attack? Ph Ph 0 Ph Michael OCH2CH3 5 OCH2CH3 OCH2CH 0 This forms... ...not this: Why? (2) In a Robinson annulation, an α,β-unsaturated carbonyl compound reacts with a carbonyl compound to afford a (new) cyclic α,β-unsaturated ketone...
Match the starting ketone or aldehyde with appropriate product
of either aldol addition or adol condensation reaction.
A ketone or an aldehyde from the list undergo either aldol addition (in a case aldol addition product can not undergo further elimination) or aldol condensation reaction in protic solvent under basic catalysis. Match the starting ketone or aldehyde with appropriate product of either aldol addition or aldol condensation reaction propanal acetaldehyde 2-ethyl-2-hydroxy-hexanal 2-methylbuta ethanal Please answer 2-ethyl-4-methyl 2-hexenal Choose 2-methyl-2-pentenal 2-ethyl-3-hydroxy-2,4-dimethyl hexanal...
(B) In the boxes below, draw the two self-condensation pro products that result from the mixture in Model 2. Use the roles reagent listed in each box to determine the products. Eation products and two mixed condensation Use the roles (Nu, Ee) for each Self Condensation Nuo = A ΕΦ = A Self Condensation Nuo = B E =B Mixed Condensation NuO = A E = B Mixed Condensation NuO = B ΕΦ = A 5. Mixed condensations can also...
1. Draw the aldol product formed from an aldol/Claisen reaction with the given starting material(s) using OH or RO in H20 or ROH. (Hint: the product of an aldol reaction is a B-hydroxy carbonyl compound or an a,b- unsaturated carbonyl compound. The a,ß-unsaturated carbonyl will be the major product unless elimination of H2O cannot form the conjugated system.) он Но, но Н,0 НО. ОН НО. он H, H НО. НО.
Draw the starting materials for the compound given below via directed aldol condensation reaction. Show the resonance structure for the following, α,β-unsaturated ketone. 1. Propose reagents or products as needed (you will need sets of reagents for arrows pointing left and 1 product for the right facing arrow). 2. H3C-SH HO
if
using piperonaldehyde, what would the answers be?
Write an equation for the Aldol reaction that takes place for the aldehyde you used for this experiment. Show the exact structures for aldehyde and product (not "general" structures with "R" groups). 1 2 Compare the crude and purified melting points from this lab with the literature melting point of your compound. What do these data say about the purity of your "green chalcone before and after purification? 14 When only a...
1. Draw the aldol product formed from an aldol/Claisen reaction with the given starting material(s) using OH or RO in H20 or ROH. (Hint: the product of an aldol reaction is a B-hydroxy carbonyl compound or an a,b- unsaturated carbonyl compound. The a,ß-unsaturated carbonyl will be the major product unless elimination of H2O cannot form the conjugated system.) MeO- MeOH ale nie ma lonky Eto- Et0 EtOH MeO- MeOH Eto- EtOH MeO- walay Meo OMe bose MeOH
5a-b
5a. Complete the reaction scheme below to show the self-aldol addition product and the self-aldol condensation product of the ketone shown: Al dol 시d'hon Aldot conunsahe b. Draw the structure of the carbanion formed which leads to the elimination of water in the condensation reaction above, and the arrow push for the loss of hydroxide ion. carbanion, and loss of OH