Which acid derivative undergoes hydrolysis to the corresponding acid slowest?
A.) Esters
B.) Amides
C.) Acid Chlorides
D.) All the same
Which acid derivative undergoes hydrolysis to the corresponding acid slowest? A.) Esters B.) Amides C.) Acid...
Whicts b. B ?.? d. D e. All of these exeept C 14. Which of the following does not represent a similarity between nitriles and carboxylic ac a. contain 3 carbon bonds to an electronegative element b. e. d. e. all of these are characteristic of both nitriles and carboxylic acids. contain two st bonds. act as electrophiles undergo nucleophilic substitution reactions 15. Which of the following is the correct assignment of the classes of the following compounds? CH3 a....
The reactivity sequence of carboxylic acid derivatives (acyl halides, anhydrides, acids, esters, amides) changes with the substituent. Acyl chlorides are most reactive, amides are least reactive. 1) Explain in detail why the reactivity changes in that sequence, 2) Where do carboxylates fit in that sequence and why? How does that impact on the way carboxylic acid reactions need to run? 3) Where do thioesters, RC(-O)SMe and acyl phosphates, RC(-O)OPO2OR fit in that sequence. Explain your decision The reactivity sequence of...
PROBLEM 21.5 Which acid derivative in each of these pairs do you think undergoes hydrolysis more quickly? Explain NH or or 0 0 NH
Draw the structures corresponding to each name: a. 4-methylheptanenitrile b. Cyclohexyl-2-methylbutanoate - Give the rules for naming acid chlorides, anhydrides, esters, amides and nitriles Which compound absorbs at the lowest wavenumber in IR? And why? (b. Which compound absorbs at the highest wavenumber in IR? And why?
For each pair of esters below specify which undergoes basic hydrolysis faster. CO2CH3 _C02CH3 Ester a: H3C0 Ester b: Na B: NEC- Ester a: CH3CO2CH(CH3)2 Ester b: CH3CO2C(CH3)3 -
Which of the following statements is NOT true about acid anhydrides? A. Acid anhydrides are more reactive than esters but less reactive than acyl chlorides. B. An acid anhydride reacts with water to form an ester product. C. Acid anhydrides eliminate a carboxylate ion as a leaving group. D. An acid anhydride is considered to have a better leaving group (i.e. weaker base) than the leaving groups of esters, carboxylic acids, and amides. A B C D
16.) Which of the following esters reacts fastest under conditions of acid-catalyzed hydrolysis? A) ethyl propanoate B) ethyl acetate C) ethyl 2-methylpropanoate D) ethyl 2,2-dimethylpropanoate
Learning Goal: To predict the hydrolysis products of amides. In the presence of a strong acid, such as HCl, and amide reacts with water to produce a carboxylic acid and an ammonium or amine salt. In the presence of a strong base, like NaOH the amide reacts to produce ammonia or an amine, and a carboxylic acid salt. Draw the carboxylic acid product of the acid hydrolysis of methanamide, shown here. Figure | H C NHA Draw the molecule on...
Which of the following is cyclohexane-1,4-dicarboxylic anhydride? Which of the following statements is true? A. Ester formation reactions are more violent and less easily controlled when anhydrides are uscd in place of acid chlorides. B. An acid chloride is most reactive of the common carboxylic acid derivatives because the chlorine atom causes a destabilizing inductive effect upon the carbon atom of the carbonyl group. C. Amides are more reactive than esters towards nucleophilic attack because nitrogen is less electronegative than...
_15. The class least reactive towards acyl substitution is a. carboxylates b. esters c. acid anhydrides d. carboxylic acids e. acid halides f. amides _ 16. Acetals protect aldehyde carbonyl groups from all of the following except: a. acidic conditions b. nucleophiles c. organometallics H h O d. basic conditions are. hydride reduction