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Echinacea is widely used as an herbal remedy for common cold, but does it work? Volunteers...

Echinacea is widely used as an herbal remedy for common cold, but does it work? Volunteers were randomly assigned to take either a placebo or an Echinacea supplement for 5 days following viral exposure. Among the 103 subjects taking Echinacea, 88 developed a cold, whereas 44 of 48 subjects taking a placebo developed a cold. (Make sure to check conditions) Construct a 97% confidence interval for the difference in the proportions of individuals developing a cold after viral exposure between the Echinacea and the placebo

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Answer #1

Here, , n1 = 103 , n2 = 48
p1cap = 0.8544 , p2cap = 0.9167


Standard Error, sigma(p1cap - p2cap),
SE = sqrt(p1cap * (1-p1cap)/n1 + p2cap * (1-p2cap)/n2)
SE = sqrt(0.8544 * (1-0.8544)/103 + 0.9167*(1-0.9167)/48)
SE = 0.0529

For 0.97 CI, z-value = 2.17
Confidence Interval,
CI = (p1cap - p2cap - z*SE, p1cap - p2cap + z*SE)
CI = (0.8544 - 0.9167 - 2.17*0.0529, 0.8544 - 0.9167 + 2.17*0.0529)
CI = (-0.1771 , 0.0525)

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