1) What type of mutation has occurred in the following?
Normal allele: 5'–GGAATGAAACAGGAACCC–3'
Mutant allele: 5'–GGAAGAAACAGGAACCC–3'
substitution
deletion of one base
insertion of one base
inversion of two bases
no mutation has occured
In this question deletion of one base is occured . As in normal allele - 5'GGAATGAAACAGGAACCC 3' in the mutant allele deletion of thymine base is occured as it can be clearly seen. In mutant allele GGAAG is present T is deleted.
So option 2 correct.
1) What type of mutation has occurred in the following? Normal allele: 5'–GGAATGAAACAGGAACCC–3' Mutant allele: 5'–GGAAGAAACAGGAACCC–3'...
A single mutation has occurred in the following DNA sequence. 5' ATG TTC CAG CCA 3' wild-type (normal) sequence 5' ATG TTC TAG CCA 3' mutant sequence a) Identify and classify the mutation according to its molecular structure (i.e., insertion, deletion base substitution (transversion), or base substitution (transition)). Briefly explain why you selected this classification. b) Identify and classify the mutation according to its functional effects (i.e., frameshift, missense, nonsense, or silent). Briefly explain why you selected this classification.
A single mutation has occurred in the following DNA sequence. 5' ATG TTG GCC CAT 3' wild-type (normal) sequence 5' ATG TTG CCC CAT 3' mutant sequence (a) Identify and classify the mutation according to its molecular structure (i.e., insertion, deletion base substitution (transversion), or base substitution (transition)). Briefly explain why you selected this classification. (1.75 marks) (b) Identify and classify the mutation according to its functional effects (i.e., frameshift, missense, nonsense, or silent). Briefly explain why you...
Due to a recessive mutation in gene A, amino acid ‘Glu’ in position 25 of polypeptide A (the wild polypeptide) is replaced by ‘Ala’. Individuals who are homozygous for the mutant allele (aa) don’t have any phenotypic alterations. Based on this observation, which of the following IS TRUE? A. The mutation has occurred in the promoter. B. The mutation has occurred in one of the introns of the encoding gene. C. The mutation was a base substitution in one of...
A single mutation has occurred in the following DNA sequence. 5' ATG AAA TTA CCA 3' wild-type (normal) sequence 5' ATG AAG TTA CCA 3' mutant sequence (a) Identify and classify the mutation according to its molecular structure (i.e., insertion, deletion base substitution (transversion), or base substitution (transition)). Briefly explain why you selected this classification (1.75 marks) (b) Identify and classify the mutation according to its functional effects (i.e., frameshift, missense, nonsense, or silent). Briefly explain why you selected this...
Describe what kind of mutation this allele has (e.g. insertion, deletion, substitution), which codon it is in, what effect it will have on the protein (e.g. nonsense missense, silent) as well as the amino acid change it will cause if it is a substitution. Refer to the genetic code. U UUU C UCU Uục Phe UCC Ser UUA UUG CUU UCA UCG CCU CCC Α UAU UAC y UGC cys UAA Stop UGA Stop UAG Stop UGG trp CGU CAC"...
Shown below are the amino acid sequences of the wild-type and three mutant forms of a short protein. Each mutation results from a single nucleotide change (transition/transversion / insertion / deletion). Use this information to answer the following questions. Hint: First, reconstruct as much as you can of the wild-type RNA sequence and then reference that sequence when analyzing the mutations. Wild type: met - gin-ala - ser-val - arg - phe Mutant 1: met - gln - pro-ser -...
Shown below are the amino acid sequences of the wild-type and three mutant forms of a short protein. Each mutation results from a single nucleotide change (transition / transversion / insertion / deletion). Use this information to answer the following questions. Hint: First, reconstruct as much as you can of the wild-type RNA sequence and then reference that sequence when analyzing the mutations. Wild type: met – gln – ala – ser – val – arg – phe Mutant 1:...
An important validation of the genetic code occurred when George Streisinger determined the amino acid sequence of bacteriophage T4 lysozyme and of mutants induced by proflavin, a dye with a planar structure that can intercalate (fit) between successive base pairs in DNA and induce frameshift mutations−that is, mutations involving additions or deletions of a single base. Streisinger and colleagues found that a particular single-base insertion mutation could be suppressed, with wild-type function restored, by a mutation that evidently involved a...
What type of mutation in HBB produces HgbS? [2 pt] substitution frameshift insertion deletion
Consider the DNA sequences shown below. What type of mutation is evident? [2 pt] wild-type: atg acc ctg ttt tca gtt aat mutant: atg acc ctg act ttt gtt aat translocation duplication inversion deletion