What type of mutation in HBB produces HgbS? [2 pt]
substitution |
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frameshift |
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insertion |
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deletion |
What type of mutation in HBB produces HgbS? [2 pt] substitution frameshift insertion deletion
Will an insertion or a deletion of three nucleotides result in a frameshift mutation? Explain why or why not.
What type of mutation will result in the production of the regular protein? neutral substitution deletion frameshift
What is the outcome of the HBB mutation that produces HgbS? [2 pt] silent nonsense radical missense conserved missense
Using these types of genetic changes: Base substitution, Transition, Transversion, Missense mutation, Nonsense mutation, Insertion, Deletion, Frameshift mutation Label these genetic changes (a-e). More than one answer may apply to each answer. a. GC->CG in the protein coding region on a gene. b. GC->TA in a GAA glutamate codon c. Loss of three bases GAA for a glutamate codon d. GC->CG in a tRNA gene e. GC->AT in the ribosome binding site of a mRNA
11. Match each type of mutation with the corresponding description. (4 points) Missense An insertion or deletion of nucleotides that are not in multiples of 3. Nonsense A mutation that does not alter the protein sequence. Silent A mutation that confers an amino acid substitution. Frameshift A mutation that confers a premature stop codon.
Which type of mutation is likely to be more harmful? Substitution O Frameshift O Silent mutation Missense Point mutation What is the coding portion of a gene called? O Exon O Transcript Intron mRNA Okasaki fragment
Mutations Worksheet-Dcletlon, Inserilon & SubstitutionThere are several types of mutations:> DELETION (a base is lost/deleted)> INSERTION (an extra base is added/inserted)- Deletion\& insertion may cause what's called a FRAMESHIFT mutation, meaning the reading "frame"changes, thus changing the amino acid sequence from this point forward > SUBSTITUTION (one base is substituted for another)- If a substitution changes the amino acid, it's called a MISSENSE mutation- If a substitution does not change the amino add, it's called a SILENT mutation- If a...
16. There is a mutation causing an insertion in the above sequence indicated by the underlined nucleotide. 5'-AAGCCATGGGCACTGGAGGTCGGATGAAACATG3'. What kind of mutation is this? a. Silent b. Missense c. Nonsense d. Frameshift e. Deletion
2. If a mutation occurs and alters the sequence CGATATGA to CGATATCA what will be the final effect - compared to the protein that was supposed to be made, how would the actual protein that is synthesized (made) look -shorter, longer or same? 3. Give the sequence of the protein that would result from such a mutation (mutation in question 4. What is the name given to such a mutation? Be specific (answer is not point mutation, deletion, insertion, substitution...
Describe what kind of mutation this allele has (e.g. insertion, deletion, substitution), which codon it is in, what effect it will have on the protein (e.g. nonsense missense, silent) as well as the amino acid change it will cause if it is a substitution. Refer to the genetic code. U UUU C UCU Uục Phe UCC Ser UUA UUG CUU UCA UCG CCU CCC Α UAU UAC y UGC cys UAA Stop UGA Stop UAG Stop UGG trp CGU CAC"...