How would you inhibit the synthesis of cocaine in plants? How would you make p-methoxy-cocaine?
Cocaine is one of the most commonly used and abused plant derived drugs in the world,. But no one have the correct information about how exactly plants produce these complex alkaloid. Alkaloids constitute a very large group of natural nitrogen containing compounds with diverse effects on the human organism. A large variety of plant produced alkaloids have strong pharmacological effects and are used as toxins,stimulants pharmaceuticals or recreational drugs, including caffeine, nicotine, morphine, quinine, strychnine, atropine, and cocaine. Most of the tropane alkaloids are used as medicines. They are commonly used as anticolic and spasmolytic in both digestive and urinary tract spastic conditions. However they are characterized by numerous contraindications and side effects. They are known to cause cardiac disorders, mainly related to heart rate disturbances and also euphoric states, depressive activity toward the CNS.
How would you inhibit the synthesis of cocaine in plants? How would you make p-methoxy-cocaine?
show how you would make this compound... 2. Show how you would make this compound by a malonic ester synthesis or an acetoacetic acid synthesis. 4-methylhexanoic acid
5. Sulfanilamides are a class of antibiotics that inhibit an enzyme involved in the synthesis of folic acid, which is necessary for the synthesis of purines and pyrimidines. A) Explain why inhibiting this enzyme would lead to the death of bacterial cells. B) Sulfanilamides are competitive inhibitors. Do you think that sulfanilamides are likely to bind reversibly or irreversibly to the enzyme? Explain your answer.
Please answer question 2. Thank you! Case Study Questions 1. Cocaine (in the form of cocaine hydrochloride) is usually consumed by drinking, snorting, or injecting, but not by smoking. However, the free base form of cocaine is smoked. What is the likely reason for this? 2. What chemical reaction(s) would occur if NaOH were used instead of baking soda to make crack cocaine? Write a mechanism for the reaction(s) proposed. 3. Locate and read the article that Professor Martinez referred...
Problem VI In plants of the genu s Primula, the K locus controls synthesis of a compound called malvidin rozygous at the K locus were crossed, producing the following distribution of progeny 1010 Make malvidin 345 Do not make malvidirn You wish to determine if the D locus (located on a different c production of malvidin as well. True-breeding plants that make malvidin (KK dd) were to true-breeding plant malvidin. synthesis, yielded the following distribution: hromosome from K), affects s...
answer question 6 with simple explanation and simple mechanism Case Study Questions I. Cocaine (in the form of cocaine hydrochloride) but not by smoking. However, the free this? une form of cocaine hydrochloride) is usually consumed by drinking, snorting, or injecting, by smoking. However, the free base form of cocaine is smoked. What is the likely reason for 2. The late comedian Richard Pryor performed a skit poking fun at himself for an caused an explosion and ignited himself attempting...
How would you change a diamond to make it a p-type semiconductor? Choose one: You can't make a diamond a semiconductor. Replace some of the carbon atoms with silicon atoms. Replace some of the carbon atoms with phosporous atoms. Replace some of the carbon atoms with aluminum atoms.
In what brain structure would you expect cocaine to have the largest effect on dopamine transmission and why?
4. How would you synthesize valine using Gabriel synthesis?
3. How would you synthesize phenylalanine using Strecker synthesis?
IT IS AN ORGANIC CHEMISTRY SYNTHESIS QUESTION 6. Synthesis: (40 pts) Show how you would carry out the following synthesis using inorganic or organic reagents containing four or less carbons. Include the reagents you would need for each step and the structure of the intermediate products formed in each step in the appropriate boxes. CI The product should be 3-chloro-3-methylhexane A) Cyclobutane 1) 2) 1) 2) como B) OH 1) 2)