Question

Mr. Smith, a patient with type I diabetes, was noncompliant for several years He was in denial about his disease and as a result, he had developed proteinuria and kidney damage. His kidney damage became significant and now he is in dialysis due to kidney failure, and he needs a kidney transplant. He has 3 brothers and 2 sisters who are all healthy.

Questions:

1. How should you begin the testing for a possible kidney transplant? _________________________________.

2. After the initial testing, name the relevant tests necessary for Mr. Smith’s condition?

1. ____________________________________________

2. _____________________________________________

3. Which virus infection, usually asymptomatic, should also be determined that could possibly impair the insulin release after renal transplant? _____________________________________

4. What are the tests required of Mr. Smith’s siblings that need to be done as possible kidney donors?

Initial examination: ___________________________________

Required testing:

1. __________________________________________

2. ___________________________________________

3. __________________________________________

4. __________________________________________

5. __________________________________________

6. ___________________________________________

7. ____________________________________________

Answer 1

1) different type of testing is done in order to proceed for kidney transplant

- blood testing ( blood group)

Tissue testing ( MHC typing)

Cross matching

Other test includes physical examination, 24 hr urine analysis and CT

2) test specific for Mr. Smith

First of all blood group and HLA typing is mist essential. Apart of this blog sugar should be controlled

And BP should be controlled before transplant

3) testing for BK virus is recommended by DNA testing in the urine of patient for every one to three month for initial first two year and later annually until the fifth year of transplantation is recommended.

4) requirement for kidney doners

- good physical and mental health

-atcleast of 18 year age

- BMI less than 35

- must be in family to match maximum HLA

- normal kidney function

- compatable blood group.

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