I know that Grignard reagents can react with alcohol, BUT why can't we generate a Grignard...
I know that Grignard reagents can react with alcohol, BUT why can't we generate a Grignard reagent from a molecule containing an OH functional group? Could you use an example or a mechanism to explain this concept?
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I know that Grignard reagents can react with alcohol, BUT why
can't we generate a Grignard...
Grignard reagent THE GRIGNARD REAGENT-PREPARATION AND REACTION In this experiment, you will prepa...
i need help with the prelab questions please
Grignard reagent THE GRIGNARD REAGENT-PREPARATION AND REACTION In this experiment, you will prepare a Grignard reagent, phenyl magnesium bromide, from bromobenzene and magnesium metal. The Grignard reagent will then react with methyl benzoate to form triphenylmethanol. Introduction Grignard reagents, such as organomagnesium halides, were discovered in 1910 by French chemist Victor Grignard. The Grignard reaction is one of the most general methods for carbon- carbon bond formation in all of organic chemistry....
You can use an infinite amount of starting material, grignard reagents seem to be the best...
You can use an infinite amount of starting material,
grignard reagents seem to be the best way to break them apart and
use them later in the reaction.
For D you can use any 1 Carbon reagent that does not
originate from the starting molecule.
Q1. Synthesize the following product from the given starting compounds. This will require more than one step. You may use any organic or inorganic reagent to carry out this synthesis but all source of carbon...
Total Points:/36 Section 1: Multiple Choice (6 pts) AIkyl halides can be converted into Grignard reagents...
Total Points:/36 Section 1: Multiple Choice (6 pts) AIkyl halides can be converted into Grignard reagents by which of the following methods? 1. a. Retluxing alky I halide and adding Mg metal in Alcohol solution. b. Reluxing with MgC solution c. Warming solution and adding Mg powder in dry Diethyl Ether. d. A and C, but not B. 2. In the Nylon experiment, why was NaOH added to the aqueous layer? Catalyze reaction Increase reaction rate Neutralize HCl as it...
10. We learned in class that epoxides undergo ring-opening reactions in the presence of strong nucleophiles....
10. We learned in class that epoxides undergo ring-opening reactions in the presence of strong nucleophiles. Grignard reagents can serve as suitable nucleophiles for ring-opening of ethylene oxide. This reaction serves as an efficient strategy for adding carbon chain length and a hydroxyl functionality for synthetic purposes. RMgX + BVOH + HOMEX Grignard reagent ethylene oxide 1 alcohol (after aqueous work-up) a. Draw a mechanism for the reaction of isopropyl magnesium chloride with ethylene oxide. b. Show how a Grignard...
IlI. Grignard Reagents Circle the molecules that can be made into a Grignard reagent. Briefly explain...
IlI. Grignard Reagents Circle the molecules that can be made into a Grignard reagent. Briefly explain why you did not select some of the molecules Br Br CH Br Br Он но
In lecture we discussed that you can't do a Grignard reaction with aniline. Why does this...
In lecture we discussed that you can't do a Grignard reaction with aniline. Why does this derivative of aniline work? Using the internet, find exact structures for the two carbonyl containing compounds (ethyl carbonate & methyl benzoate).
This is for the Grignard Reaction laboratory. Please help me answer this question, much appreciated. 1....
This is for the Grignard Reaction laboratory. Please help me answer this question, much appreciated. 1. If a student performing Laboratory with Grignard reaction accidently used acetone as the reaction solvent instead of diethyl ether, what would the major organic product(s) be? Draw the structure of the product(s) (no mechanism necessary). b. What was the purpose of adding magnesium sulfate in this experiment? c. Grignard reagents react with both aldehyde and ketone functional groups. How do you predict the reaction...
In chapter 9 we learned how to make acetylide anions and use them as nucleophiles. In...
In chapter 9 we learned how to make
acetylide anions and use them as nucleophiles. In order to use this
method, we will need to transform the alcohol to a different
functional group that would make the carbon a better electrophile.
Come up with a method (can be done in 2 steps) to produce the
desired product from cyclopentanol (6 points)
4) The following image shows the general structure of a steroid: Steroids can be utilized in the biological systems...
7) Name four reagents you can use to dry solvent. Why do we use magnesium sulfate...
7) Name four reagents you can use to dry solvent. Why do we use
magnesium sulfate in this lab instead of them?
Introduction Alkyl halides can be prepared from alcohols by reactions with hydrogen halides (HCI, HBr, or HI) via nucleophilic substitution. In this type of reaction, the nucleophile displaces a leaving group from a carbon atom of an organic substrate (here the alcohol once protonated). Both electrons of the new bond to the carbon are provided by the nucleophile...
Grignard reagent THE GRIGNARD REAGENT-PREPARATION AND REACTION In this experiment, you will prepa...
i need help with the postlab questions please
Grignard reagent THE GRIGNARD REAGENT-PREPARATION AND REACTION In this experiment, you will prepare a Grignard reagent, phenyl magnesium bromide, from bromobenzene and magnesium metal. The Grignard reagent will then react with methyl benzoate to form triphenylmethanol. Introduction Grignard reagents, such as organomagnesium halides, were discovered in 1910 by French chemist Victor Grignard. The Grignard reaction is one of the most general methods for carbon- carbon bond formation in all of organic chemistry....
i need help with the prelab questions please
Grignard reagent THE GRIGNARD REAGENT-PREPARATION AND REACTION In this experiment, you will prepare a Grignard reagent, phenyl magnesium bromide, from bromobenzene and magnesium metal. The Grignard reagent will then react with methyl benzoate to form triphenylmethanol. Introduction Grignard reagents, such as organomagnesium halides, were discovered in 1910 by French chemist Victor Grignard. The Grignard reaction is one of the most general methods for carbon- carbon bond formation in all of organic chemistry....
You can use an infinite amount of starting material,
grignard reagents seem to be the best way to break them apart and
use them later in the reaction.
For D you can use any 1 Carbon reagent that does not
originate from the starting molecule.
Q1. Synthesize the following product from the given starting compounds. This will require more than one step. You may use any organic or inorganic reagent to carry out this synthesis but all source of carbon...
Total Points:/36 Section 1: Multiple Choice (6 pts) AIkyl halides can be converted into Grignard reagents by which of the following methods? 1. a. Retluxing alky I halide and adding Mg metal in Alcohol solution. b. Reluxing with MgC solution c. Warming solution and adding Mg powder in dry Diethyl Ether. d. A and C, but not B. 2. In the Nylon experiment, why was NaOH added to the aqueous layer? Catalyze reaction Increase reaction rate Neutralize HCl as it...
10. We learned in class that epoxides undergo ring-opening reactions in the presence of strong nucleophiles. Grignard reagents can serve as suitable nucleophiles for ring-opening of ethylene oxide. This reaction serves as an efficient strategy for adding carbon chain length and a hydroxyl functionality for synthetic purposes. RMgX + BVOH + HOMEX Grignard reagent ethylene oxide 1 alcohol (after aqueous work-up) a. Draw a mechanism for the reaction of isopropyl magnesium chloride with ethylene oxide. b. Show how a Grignard...
IlI. Grignard Reagents Circle the molecules that can be made into a Grignard reagent. Briefly explain why you did not select some of the molecules Br Br CH Br Br Он но
In lecture we discussed that you can't do a Grignard reaction with aniline. Why does this derivative of aniline work? Using the internet, find exact structures for the two carbonyl containing compounds (ethyl carbonate & methyl benzoate).
In chapter 9 we learned how to make
acetylide anions and use them as nucleophiles. In order to use this
method, we will need to transform the alcohol to a different
functional group that would make the carbon a better electrophile.
Come up with a method (can be done in 2 steps) to produce the
desired product from cyclopentanol (6 points)
4) The following image shows the general structure of a steroid: Steroids can be utilized in the biological systems...
7) Name four reagents you can use to dry solvent. Why do we use
magnesium sulfate in this lab instead of them?
Introduction Alkyl halides can be prepared from alcohols by reactions with hydrogen halides (HCI, HBr, or HI) via nucleophilic substitution. In this type of reaction, the nucleophile displaces a leaving group from a carbon atom of an organic substrate (here the alcohol once protonated). Both electrons of the new bond to the carbon are provided by the nucleophile...
i need help with the postlab questions please
Grignard reagent THE GRIGNARD REAGENT-PREPARATION AND REACTION In this experiment, you will prepare a Grignard reagent, phenyl magnesium bromide, from bromobenzene and magnesium metal. The Grignard reagent will then react with methyl benzoate to form triphenylmethanol. Introduction Grignard reagents, such as organomagnesium halides, were discovered in 1910 by French chemist Victor Grignard. The Grignard reaction is one of the most general methods for carbon- carbon bond formation in all of organic chemistry....
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