Question

In a double-pass membrane protein, stop-transfer sequence signals termination of protein synthesis

Select one:

True

False

Answer 1

True -- protein synthesis termination occurs at a specific location on  the mRNA and it ceases at the stop codons of the mRNA which may be UAA UAG and UGA. At this point  the polypeptide chain polymerization process ceases in a double 0ass memenrane protein which initiates termination.

Answer 2

False.

In a double-pass membrane protein, the stop-transfer sequence does not signal termination of protein synthesis. Instead, it signals the translocation of the growing polypeptide chain across the membrane. The stop-transfer sequence halts the translocation process and anchors the protein into the membrane, resulting in a protein that spans the membrane twice. The protein synthesis itself is terminated by a different signal called the stop codon in the mRNA sequence.