A muscle tissue contains 2.5 mM lactic acid or lactate. Let's assume that the pH is...
A muscle tissue contains 2.5 mM lactic acid or lactate. Let's assume that the pH is 7. a. If the ([NAD+]/[NADH]) = 1.0, what is the concentration of pyruvate at equilibrium? b. If the glucose concentration in the muscle tissue is 3.5 mM at pH 7, what ratio of ([ATP]/[ADP]) is maintained in the muscle tissue at equilibrium?
Homework Answers
a. GLUCOSE 
2 PYRUVATE 
2 LACTATE
Since, 2 molar lactate is formed from 2 molar pyruvate, to form 2.5 mM lactate, the cell must contain 2.5 mM pyruvate.
b. In every cycle, ratio of ATP and ADP is 1.
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A muscle tissue contains 2.5 mM lactic acid or lactate. Let's
assume that the pH is...
A muscle tissue contains 2.5 mM lactic acid or lactate. Let's assume that the pH is...
A muscle tissue contains 2.5 mM lactic acid or lactate. Let's assume that the pH is 7. If you need other assumptions, state them. a. If the ([NAD+]/[NADH]) = 1.0, what is the concentration of pyruvate at equilibrium? b. If the glucose concentration in the muscle tissue is 3.5 mM at pH 7, what ratio of ([ATP]/[ADP]) is maintained in the muscle tissue at equilibrium? c. Why did we need to know the ratio of (NAD+]/[NADH] to answer question 1a?
14. Lactate dehydrogenase (LDH) catalyzes conversion of pyruvate into L-lactate in muscle tissue. What is the...
14. Lactate dehydrogenase (LDH) catalyzes conversion of pyruvate into L-lactate in muscle tissue. What is the AG' (in kJ/mol) for the forward reaction catalyzed by LDH at an average adult body temperature of 37 °C? Equilibrium concentrations of the reactants and products are given below for each of the components. You must show your calculations. (4 pts) 00 0. 0 LDH + NADH + H = - HOCH + NAD 0 CH3 5uM 0.75 UM 7.8 UM Pyruvate 17.5 UM...
Equal volumes of 200 mM lactic acid and 200 mM potassium lactate are mixed to make...
Equal volumes of 200 mM lactic acid and 200 mM potassium lactate are mixed to make a buffer. The pKa of lactic acid is 3.86 (a) Determine the pH of this buffer and its final concentration. [4 marks] (b) Calculate the concentrations of the buffer components after acid or base is added to bring the pH to 4.5. Assume a negligible change in volume. 6 marks]
Lactic acid is a simple organic acid that is somewhat stronger than acetic acid. The lactate...
Lactic acid is a simple organic acid that is somewhat stronger than acetic acid. The lactate ion is the conjugate base of lactic acid and is one product of animal (including human) metabolism. Ka for lactic acid is 1.38 x 10-4. If the resting amount of lactate in blood is 2.0 mM and typical blood pH is 7.40, what is the lactic acid concentration in blood? Calculate the pH of a 0.0100 M solution of lactic acid. Calculate the pH...
QUESTION 12 A eukaryotic cell can use glucose (C6H1206) and hexanoic acid (C6H1402) as fuels for...
QUESTION 12 A eukaryotic cell can use glucose (C6H1206) and hexanoic acid (C6H1402) as fuels for cellular respiration. On the basis of their structural formulas, which of these is more reduced? a hexanoic acid glucose Both are oxidized Cannot be determined QUESTION 13 Which of the substances in question 12 releases less energy per gram on complete combustion to CO2 and H20? Hexanoic acid O glucose Both release the same amount of energy as they are in equilibrium Cannot be...
Lactic acid, which builds up in muscle tissue upon strenuous exercise, is partially dissociated in aqueous...
Lactic acid, which builds up in muscle tissue upon strenuous exercise, is partially dissociated in aqueous solution: The following equilibrium concentrations were measured at 25 ∘C: Lactic acid [C3H6O3]=9.64×10−2M;[H+]=3.65×10−3M; Lactate ion [C3H5O3−]=3.65×10−3M. Calculate the value of the equilibrium constant.
- Attempt 1 ar Respiration and fermentation summary ③ 3 ott Part C - Fermentation -...
- Attempt 1 ar Respiration and fermentation summary ③ 3 ott Part C - Fermentation - ATP production in the absence of oxygen Under anaerobic conditions (a lack of oxygen), glycolysis continues in most cells deste the fact that oxidative phosphorylation stops and its production of NAD (which is needed as an input to glycolysis) also stops. The diagram Vlustrates the process of fermentation which is used by many cols in the absence of oxygen In fermentation, the NADH produced...
help A monoprotic weak acid, HA, dissociates in water according to the reaction HA(aq) = (aq)...
help
A monoprotic weak acid, HA, dissociates in water according to the reaction HA(aq) = (aq) + A (aq) The equilibrium concentrations of the reactants and products are [HA] = 0.180 M, H+] = 3.00 x 10-4 M, and A) = 3.00 x 10-4 M. Calculate the value of pK, for the acid HA. pKg = During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced from the breakdown of...
what is the ratio of lactic acid (Ka-1.37x10-4) to lactate in a solution with pH-3.967 1st...
what is the ratio of lactic acid (Ka-1.37x10-4) to lactate in a solution with pH-3.967 1st attempt Ihl See Periodic Table Write your ratio out as a number containing a decimal. (lactic acid) lactate]
What is the ratio of lactic acid (Ka = 1.37x10-4) to lactate in a solution with pH = 4.33?
What is the ratio of lactic acid (Ka = 1.37x10-4) to lactate in a solution with pH = 4.33?
14. Lactate dehydrogenase (LDH) catalyzes conversion of pyruvate into L-lactate in muscle tissue. What is the AG' (in kJ/mol) for the forward reaction catalyzed by LDH at an average adult body temperature of 37 °C? Equilibrium concentrations of the reactants and products are given below for each of the components. You must show your calculations. (4 pts) 00 0. 0 LDH + NADH + H = - HOCH + NAD 0 CH3 5uM 0.75 UM 7.8 UM Pyruvate 17.5 UM...
Equal volumes of 200 mM lactic acid and 200 mM potassium lactate are mixed to make a buffer. The pKa of lactic acid is 3.86 (a) Determine the pH of this buffer and its final concentration. [4 marks] (b) Calculate the concentrations of the buffer components after acid or base is added to bring the pH to 4.5. Assume a negligible change in volume. 6 marks]
QUESTION 12 A eukaryotic cell can use glucose (C6H1206) and hexanoic acid (C6H1402) as fuels for cellular respiration. On the basis of their structural formulas, which of these is more reduced? a hexanoic acid glucose Both are oxidized Cannot be determined QUESTION 13 Which of the substances in question 12 releases less energy per gram on complete combustion to CO2 and H20? Hexanoic acid O glucose Both release the same amount of energy as they are in equilibrium Cannot be...
- Attempt 1 ar Respiration and fermentation summary ③ 3 ott Part C - Fermentation - ATP production in the absence of oxygen Under anaerobic conditions (a lack of oxygen), glycolysis continues in most cells deste the fact that oxidative phosphorylation stops and its production of NAD (which is needed as an input to glycolysis) also stops. The diagram Vlustrates the process of fermentation which is used by many cols in the absence of oxygen In fermentation, the NADH produced...
help
A monoprotic weak acid, HA, dissociates in water according to the reaction HA(aq) = (aq) + A (aq) The equilibrium concentrations of the reactants and products are [HA] = 0.180 M, H+] = 3.00 x 10-4 M, and A) = 3.00 x 10-4 M. Calculate the value of pK, for the acid HA. pKg = During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced from the breakdown of...
what is the ratio of lactic acid (Ka-1.37x10-4) to lactate in a solution with pH-3.967 1st attempt Ihl See Periodic Table Write your ratio out as a number containing a decimal. (lactic acid) lactate]
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