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A muscle tissue contains 2.5 mM lactic acid or lactate. Let's assume that the pH is...

A muscle tissue contains 2.5 mM lactic acid or lactate. Let's assume that the pH is 7. If you need other assumptions, state them.

a. If the ([NAD+]/[NADH]) = 1.0, what is the concentration of pyruvate at equilibrium?

b. If the glucose concentration in the muscle tissue is 3.5 mM at pH 7, what ratio of ([ATP]/[ADP]) is maintained in the muscle tissue at equilibrium?

c. Why did we need to know the ratio of (NAD+]/[NADH] to answer question 1a?

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Answer #1

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la a pyruvate + NADH NAD+ + lactate (NADI min in K [NAD+ ] [lactate} = 2.5*103M XI [pyruvate] [NADH pyruvate Pka = pH = 7 (gi

c) the ratio of NAD+ and NADH are needed as lactic acid and NAD+ are production of pyruvate and NADH.

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