Question

Explain protein denaturation and discuss how the physical and biological properties are altered after denaturation

Answer 1

ANS-----The highly organized structures of proteins are truly masterworks of chemical architecture. But highly organized structures tend to have a certain delicacy, and this is true of proteins. Denaturation is the term used for any change in the three-dimensional structure of a protein that renders it incapable of performing its assigned function. following point responsible for denaturation Physical agents: • Heat • Violent shaking or agitation • Hydrostatic pressure • UV radiation Chemical agents: • Acids and alkalis • Organic solvents • Salts of heavy metals • Chaotropic agents • Detergents • Altered pH 10 we now that Protein molecules carry out many important tasks in living systems. Most important, the majority of proteins are quite specific about which task they perform. Protein structure is what dictates this specificity, and the three-dimensional (tertiary) structure is particularly important. When this specific three-dimensional structure is disrupted, the protein loses its functionality and is said to have undergone denaturation. during denaturation of proteins 3D structure distrub ,that's why the  the physical and biological properties are altered after denaturation ***** here something about 3D structure of amino acid [1]  the three-dimensional structure of a protein is determined by its amino acid sequence [2] the function of a protein depends upon its three-dimensional structure   [3]the three-dimensionalstructure of a protein is unique