3. Many biological macromolecules undergo a transition called denaturation, where the system unfolds. For a protein at a pH 2 the change in enthalpy associated to denaturation is 418 kJ/mol and th...
Question 4 Many biological macromolecules undergo a transition called denaturation. Denaturation is a process whereby a structured, biologically active molecule, called the native form, unfolds or becomes unstructured and biologically inactive. The equilibrium is Native (folded) # denatured (unfolded) For a protein at pH = 2 the enthalpy change associated with denaturation is AH° = 418.0 kJ/mol and the entropy change is AS° = 1.3 kJ/K.mol both at 298.15K (a) Calculate the Gibbs free energy of denaturation of the protein...
. For a protein denaturation at at T=310 K and P=1 atm, the enthalpy change is 911 kJ/mol and the entropy change is 3.12 J/(mol K). Calculate the Gibbs energy change at T=310K and P=1 atm. Calculate the Gibbs energy change at T=310 K and P=1000 bar. Assume for the denaturation volume change V=3 mL/mol.
Thermodynamics 1) The enthalpy of vaporization of water ∆H = -25 kJ mol-1 at T = 45 °C. When water V = 15 cm3 in an open vessel evaporates at this temperature, calculate the change in entropy of the surroundings. 2) For a given reaction, ∆H = 25 kJ and ∆S = 50 J/K. Above what temperature will this reaction occur spontaneously? 3) At T = 15°C a certain protein denatures reversibly with ∆H = 30 kJ/mol. The system is...