Question

I want to design a microchannel which incorporates a biological sensor. To work, the sensing element must be exposed to enough analyte to reach its detection threshold. This sensor has a detection threshold of 0.1 micrograms of cocaine. My sample contains cocaine at a concentration of 100 nM. Due to size constraints of the chip and sensor, the channel must be 1 mm long. If I want to determine if this sample has cocaine within 20 minutes, what is the necessary flowrate? What is the pressure drop needed to drive this in a 10 micron by 10 micron channel? What bonding methods could be used for this? What if the channel was 20 micron by 20 micron? Given: the molecular weight of Cocaine is 303.353 g/mol.

Answer 1