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What will happen if the levels of CO2 in the bloodstream increases? 1. Hemoglobin-oxygen affinity will...

What will happen if the levels of CO2 in the bloodstream increases?

1. Hemoglobin-oxygen affinity will go up

2. Hemoglobin-oxygen affinity will go down

3. Hemoglobin-oxygen affinity will be unchanged

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Answer #1

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2. Hemoglobin-oxygen affinity will go down

Explanation : Increase in CO2 concentration in the blood shifts the oxygen hemoglobin dissociation curve towards right side that reduces oxygen hemoglobin affinity. As a result more oxygens are released at tissue level. This compensates the demand of oxygen by the tissue.

Due to increased CO2, it competes with oxygen for binding to Hb hence oxygen affinity is reduced.

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