What's the function of CDK6? Whats CDK6 role in the cell cycle? (In-depth explanation, not just...
What's the function of CDK6? Whats CDK6 role in the cell cycle? (In-depth explanation, not just that its needed during G1/S) What are the other major proteins CDK6 interacts with to complete its function?
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What's the function of CDK6? Whats CDK6 role in the cell cycle?
(In-depth explanation, not just...
QUESTION 1 Which of these proteins is responsible for preventing cell cycle progression if DNA damage...
QUESTION 1 Which of these proteins is responsible for preventing cell cycle progression if DNA damage is detected? Rb p53 ras E7 1 points QUESTION 2 Which of the following is a proto-oncogene? Cyclin Cdk ras All of the above 1 points QUESTION 3 The photograph below shows a chromosome. In what phase of the cell cycle was the cell from which this chromosome taken? G1 S G2 M Interphase 1 points QUESTION 4 Which of the...
Explain the central role played by CdK (cell cycle-dependent kinases) in the transition from G1 to...
Explain the central role played
by CdK (cell cycle-dependent kinases) in the transition from G1 to
S and preRC to preIC at DNA origins of replication. Use the diagram
below for help
RC ORC Cyclin A/B+ Cdk APC Licensed DNA Rb DNA replication MCM ORC Rb S G1 D cyclins Cdk4/6 Cyclin A Cdk2 Cyclin E+Cdk2 ORC DNA licensing inactivation Skp2 CUL4 → Cok
Question 2 4 pts Match the phase of the cell cycle with the correct function. Confirming...
Question 2 4 pts Match the phase of the cell cycle with the correct function. Confirming that [Choose DNA replication occured properly DNA replication occurs [Choose [Choose DNA separated into two identical (daughter) cells Initial cell growth occurs Mitosis 10:19 | TE canvas.cwu.edu Question 2 4 pts Match the phase of the cell cycle with the correct function. G1 Confirming that DNA replication occured properly S phase DNA replication occurs Mitosis DNA separated into two identical (daughter) cells Initial cell...
QUESTION 7 If you inject a G1 cell that contains 36 chromosomes with a G2/M cyclin,...
QUESTION 7 If you inject a G1 cell that contains 36 chromosomes with a G2/M cyclin, what would happen? (hint - look at slide with cell fusion experiments) The G1 cell would complete mitosis with daughter cells that have 18 chromosomes each The G1 cell would enter mitosis but arrest at the spindle checkpoint because the chromosomes were not properly replicated The G1 cell would complete mitosis with daughter cells that have 36 chromosomes each The G1 cell would go...
CHAPTER 12 THE CELL CYCLE Study Questions The Key Roles of Cell Division 1. Why do...
CHAPTER 12 THE CELL CYCLE Study Questions The Key Roles of Cell Division 1. Why do cells divide? 2. What are the major events of eukaryotic cell division that enable the genome of one cell to be passed on to two daughter cells? 3. How do chromosomal numbers change throughout the human life cycle? The Mitotic Cell Cycle 4. What are the phases of the cell cycle? What is the sequence of events that occurs during each phase? 5. What...
QUESTION 1 A gene that encodes a protein that stimulates progression of the cell cycle is...
QUESTION 1 A gene that encodes a protein that stimulates progression of the cell cycle is known as a proto-oncogene. True False QUESTION 2 Cytokinesis occurs after which stage or phase of the cell cycle? a. G2 b. S c. G0 d. G1 e. M phase QUESTION 3 During cell-cycle checkpoints, protein kinases known as CDKs phosphorylate target proteins only when they associate with a cyclin. True False QUESTION 4 During mitosis, many of the spindle fibers attach to chromosomes...
Cancer biology 23. The levels of these proteins fluctuate dramatically as cells progress through the cell...
Cancer biology
23. The levels of these proteins fluctuate dramatically as cells progress through the cell cycle. These fluctuations are tightly coordinated with the schedule of advances through the various cell cycle phases. For a particular subtype, extracellular signals, notably those conveyed by growth factors, strongly influence their levels. These proteins are: cdc25-like phosphatases b. Cdk kinases c. Protectins d. Cyclins 24. Which of the following best describes the biochemistry that correlates to one of the cell cycle functions of...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of the APC, which in a ubiquitin E3 ligase, in the control of the metaphase cyclin (cyclin B) and the timing of events. To look at this you start by synchronizing your cells in G1 and examining the levels of Cyclin B over time. The APC usually works on cyclin B during anaphase. RBX57 is a substrate for Cylcia...
QUESTION 7 Quiescent cells are cells which are in Go stage of the cell cycle. What stimulus would be required for these...
QUESTION 7 Quiescent cells are cells which are in Go stage of the cell cycle. What stimulus would be required for these Go cells to re-enter the cell cycle? What event(s) occur after stimulation? Hint: Your complete response should include genes being transcribed and the different factors associated with that process ▼T·-·-▼ TTT Arial 3 (12pt) ▼ QUESTION 8 Consider that same cells in GO. In order for these cells to divide normally. they would need to renter G1 and...
Inspired by Lee Hartwell's Nobel Prize (2001), you decide to study cell cycle regulation in yeast....
Inspired by Lee Hartwell's Nobel Prize (2001), you decide to study cell cycle regulation in yeast. You know that the expression of a cell cycle-associated kinase, Cdk24p, changes throughout the cell cycle, being very high in G 1/S and low in G2/M. Nevertheless, mRNA levels for CDK24 are constant throughout the cell cycle. You decide to study how this regulation occurs. You isolate a temperature sensitive mutant cell linethat fails to divide at the non-permissive temperature and notice that Cdk24p...
Explain the central role played
by CdK (cell cycle-dependent kinases) in the transition from G1 to
S and preRC to preIC at DNA origins of replication. Use the diagram
below for help
RC ORC Cyclin A/B+ Cdk APC Licensed DNA Rb DNA replication MCM ORC Rb S G1 D cyclins Cdk4/6 Cyclin A Cdk2 Cyclin E+Cdk2 ORC DNA licensing inactivation Skp2 CUL4 → Cok
Question 2 4 pts Match the phase of the cell cycle with the correct function. Confirming that [Choose DNA replication occured properly DNA replication occurs [Choose [Choose DNA separated into two identical (daughter) cells Initial cell growth occurs Mitosis 10:19 | TE canvas.cwu.edu Question 2 4 pts Match the phase of the cell cycle with the correct function. G1 Confirming that DNA replication occured properly S phase DNA replication occurs Mitosis DNA separated into two identical (daughter) cells Initial cell...
QUESTION 7 If you inject a G1 cell that contains 36 chromosomes with a G2/M cyclin, what would happen? (hint - look at slide with cell fusion experiments) The G1 cell would complete mitosis with daughter cells that have 18 chromosomes each The G1 cell would enter mitosis but arrest at the spindle checkpoint because the chromosomes were not properly replicated The G1 cell would complete mitosis with daughter cells that have 36 chromosomes each The G1 cell would go...
CHAPTER 12 THE CELL CYCLE Study Questions The Key Roles of Cell Division 1. Why do cells divide? 2. What are the major events of eukaryotic cell division that enable the genome of one cell to be passed on to two daughter cells? 3. How do chromosomal numbers change throughout the human life cycle? The Mitotic Cell Cycle 4. What are the phases of the cell cycle? What is the sequence of events that occurs during each phase? 5. What...
Cancer biology
23. The levels of these proteins fluctuate dramatically as cells progress through the cell cycle. These fluctuations are tightly coordinated with the schedule of advances through the various cell cycle phases. For a particular subtype, extracellular signals, notably those conveyed by growth factors, strongly influence their levels. These proteins are: cdc25-like phosphatases b. Cdk kinases c. Protectins d. Cyclins 24. Which of the following best describes the biochemistry that correlates to one of the cell cycle functions of...
1) You are a studying the prog ression of cells through the cell cycle. You are particularly interested in the role of the APC, which in a ubiquitin E3 ligase, in the control of the metaphase cyclin (cyclin B) and the timing of events. To look at this you start by synchronizing your cells in G1 and examining the levels of Cyclin B over time. The APC usually works on cyclin B during anaphase. RBX57 is a substrate for Cylcia...
QUESTION 7 Quiescent cells are cells which are in Go stage of the cell cycle. What stimulus would be required for these Go cells to re-enter the cell cycle? What event(s) occur after stimulation? Hint: Your complete response should include genes being transcribed and the different factors associated with that process ▼T·-·-▼ TTT Arial 3 (12pt) ▼ QUESTION 8 Consider that same cells in GO. In order for these cells to divide normally. they would need to renter G1 and...
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