Question

What are examples of monosomy and trisomy disorders (besides Kleinfelters and Turners)

Answer 1

QUESTION-

ANSWER

Examples of monosomy and trisomy disorders (besides Kleinfelters and Turners).

MONOSOMY DISORDER

Monosomy disorder is one of the chromosomal numerical abnormalities. In Numerical abnormalities, the cell contains 45 or 47 chromosomes instead of normal 46 chromosomes.

In monosomy, one copy of the chromosome is present instead of the usual two.

EXAMPLE-

Turner's syndrome is the only viable monosomy which is known till date.

TRISOMY DISORDER

In trisomy one extra chromosome is found.

There are so many viable trisomic conditions

1. Down syndrome

• Trisomy 21, 47 chromosomes.
• An extra copy of chromosome 21 is found in the cell.
• Affects 1:1700 children.

Characteristics-

• baby born with this syndrome has heart defects, susceptible to respiratory disorders.
• Prone to Alzheimers's and leukemia.
• Sexually underdeveloped.
• Mental retardation.

2. Edward's syndrome

• Trisomy 18
• Affects 1: 1100 children.

Characteristics-

• defects of the kidneys, heart, lungs, diaphragm.
• cleft palate
• microcephaly
• club feet and webbing between fingers.
• neural tube defect.
• sex organs are defective.

3. Patau syndrome

• Trisomy 13
• Affects 1:3000 children.

Characteristics-

• microcephaly i.e small skull.
• additional fingers.
• malfunction of sex organs.
• cleft lip or palate.
• the abnormal opening of the skull.
• Eye Defect.

GOOD LUCK.