Question

Which of the following mRNA codons can be recognized by the tRNA anticodon 3' GCI 5'?...

Which of the following mRNA codons can be recognized by the tRNA anticodon 3' GCI 5'? choose all that apply

a. 5' UGC 3'

b. 5' CGA 3'

c. 5' CGG 3'

d. 5' CGU 3'

e. 5' CGC 3'

I got b,d, and e as my answers but I just want to make sure im doing the wobble correctly.

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Answer #1

Inosine I can basepair with A, C, U and wobble basepairing is due to third base in the codon, 3` end of the anticodon basepairs with the 5` end of the codon, so the first 2 bases of the codon has to complementary to 2 bases at the 3` so the sequence of the first two bases of codon are C and G it is complementary to G and C at the 3` end of the anti-codon, so the third base in the codon can be A, C, U which can basepair with the I, so the possible codons to which the 3`-GCI-5` can basepair with are

b. 5' CGA 3',

d. 5' CGU 3'

e. 5' CGC 3'

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