2,3-BPG is a product of glycolysis, consequently, it can be metabolized as a part of glycolysis...
2,3-BPG is a product of glycolysis, consequently, it can be metabolized as a part of glycolysis when glycolytic intermediates are low. Blood that has been stored for long periods of time may be low in 2,3-BPG (for this reason) if no precautions are taken. What happens if such blood is used in transfusion?
Homework Answers
- 2,3-biphosphoglycerate (BPG) promotes hemoglobin transition from a high oxygen affinity state to a low oxygen affinity state.
- During storage of blood, RBCs rapidly lose 2,3-biphosphoglycerate leading to an increase in the affinity for oxygen and a temporary impairement of oxygen transport.
- Decreased survival and organ function have been demonstrated with transfusion of low 2,3-DPG red cells.
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2,3-BPG is a product of glycolysis, consequently, it can be
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