What are the modes of asymmetry in the membrane and how are they maintained?
The membranes are asymetric due to the asymetric type of insertion of proteins that are synthesized by the former membranes. The phospholipids in the membrane are shared in a asymmetric way on the lipid bilayer in a phenomenon known as membrane phospholipid asymetry. The 3 types of translocases- scramblases, floppases, & filppases, which are proteins helps in moving lipids among the monolayers & thus maintains & modifies the membrane asymmetry.
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What are the modes of asymmetry in the membrane and how are they maintained?
Animals exploit the phospholipid asymmetry of their plasma membrane to distinguish between live cells and dead ones. When animal cells undergo a form of programmed cell death called apoptosis, phosphatidylserine-a phospholipid that is normally confined to the cytosolic monolayer of the plasma membrane-rapidly translocates to the extracellular, outer monolayer. The presence of phosphatidylserine on the cell surface serves as a signal that helps direct the rapid removal of the dead cell. How might a cell actively engineer this phospholipid redistribution?...
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