Question

How might an XY person with a deletion of the SRY gene be distinguished from a person with androgen-insensitivity syndrome?

Answer 1

These two things are almost similar.

XY person with a deletion of the SRY gene means If the SRY is present, then the process of development leads to a male. If the SRY is absent, then the embryo will become female. If during meiosis the SRY ends up crossing over to the X chromosome, then an XX offspring (normally a female) will end up developing into a male because it has the SRY that causes maleness.

And in case of androgen insensitivity syndrome means Androgen insensitivity syndrome (AIS) is when a person who is genetically male (who has one X and one Y chromosome) is resistant to male hormones (called androgens). As a result, the person has some or all of the physical traits of a woman, but the genetic makeup of a man. Androgen insensitivity syndrome is a condition that affects sexual development before birth and during puberty. People with this condition are genetically male, with one X chromosome and one Y chromosome in each cell. Because their bodies are unable to respond to certain male sex hormones (called androgens), they may have mostly female external sex characteristics or signs of both male and female sexual development.

So, as we can see these two situations can't distinguishable.