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As of 2016, Lipitor® -a drug for treating hypercholesterolemia-was the best selling pharmaceutical ever in the...

As of 2016, Lipitor® -a drug for treating hypercholesterolemia-was the best selling pharmaceutical ever in the US. Briefly explain how Lipitor® blocks cholesterol synthesis?

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Answer #1

Lipitor (atorvastatin) is a cholesterol-lowering medication or drug that comes in the statins.

Lipitor functions by arresting, 3-hydroxy-3methylglutaryl coenzyme A (HMG CoA) reductase which is an enzyme in the body that play a significant role in forming cholesterol in the liver. This action subsequently lowers the amount of cholesterol in the body.

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