Question

Question2

(A) The US Federal Drugs Administration (FDA) recently approved a drug for a rare fatal genetic disease that had only been trialled on 12 patients, without a placebo. One condition of the approval is that the company must carry out a more complete trial, even though sufferers can receive the drug because it is approved. Why will it be difficult to carry out such a trial?

(B) A recent study reported that upper class people spent less time than working class people looking at faces of others in New York street scenes. The authors used this to conclude that social class affects people’s appraisals of others. Discuss the value of this evidence, and design an experiment to better test the conclusion.

(C) Hershey and Chase used radioactively labelled viruses to show that DNA is the genetic material. Discuss the negative and positive controls implicit in their experimental design.

I'm not sure how to begin answering these questions.. they are asking for essay type answers but I'm struggling to see where to start. Help would be appreciated. Thank you !!

Answer 1

(A) It is difficult to carry out such trial since

1. the drug is being used for a Rare fatal genetic disease, thus the available objects for trial would be very rare
2. Genetic disease trial are usually accompanied with DNA sequence monitoring, which is a challenging process.
3. It will be a Time consuming process
4. It is difficult to test the defective gene
5. Patients usually not prefer to be trial object unless in worst conditions

(B) Appraisal usually refers to an act of assessing something or someone, Maybe it would be because of desire to Achieve more than their current situation, such that they could assess the quality traits of successful people they have been missing in themselves and need to cultivate such characters.

(c) POSITIVE AND NEGATIVE CONTROL IMPLICITS ON HERSEY AND CHASE EXPERIMENT -They concluded that protein was not likely to the hereditary genetic material, However, they did not made any conclusions regarding the specific functions of DNA as hereditary material and only said that it must have some undefined roles.

I hope the above answers will work out for you..!!