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PepT1 is a di-/tripeptide influx transporter in the small intestine. A patient is taking a dipeptide...

PepT1 is a di-/tripeptide influx transporter in the small intestine. A patient is taking a dipeptide conjugate of a drug that is a substrate for PepT1. If this person were to ingest the drug with other substrates of PepT1, absorption of the conjugate could ______.

a) increase

b) decrease

c) remain unaffected

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Answer #1

answer a) increase

A patient is taking a dipeptide conjugate of a drug that is a substrate for PepT1. If this person were to ingest the drug with other substrates of PepT1, absorption of the conjugate could increase.

as PepT1 is responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen , As the substrates of PepT1 increases absorption gets increased.

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