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With major component (Benzohydrol) and minor component (caffeine), explain why an acid-base reaction would be good...

With major component (Benzohydrol) and minor component (caffeine), explain why an acid-base reaction would be good to seperate the two components. Explain procedures for acid-base reaction steps that will help you achieve acid-base seperation.

Please explain why acid-base reaction would be the best option in lieu of recrystallization based on chemical principles.

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Answer #1

When the mixture of benzhydrol and caffeine is treated with dilute HCl, caffeine will get protonated and will be present in aqueous layer. While benzhydrol will remain in organic layer. The further treatment of aqueous layer with dilute NaOH will result in precipitation of pure caffeine which can be filtered by vacuum filtration. This way recrystallization can be avoided as it will not separate these two compounds.

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