Question

1. Which statement about mRNA splicing is not accurate?
   1. Splicing is carried out by tRNA and associated proteins
   2. The C-terminal tail domain of RNA polymerade coordinates the processing (including splicing) of mRNA.
   3. The 2’ –OH in ribose is used during the splicing reaction.
   4. Alternative splicing can produce different proteins from the same genetic sequence in DNA
2. Which describes the cellular role of chaperone proteins?
   1. Guide nascent proteins to their final destination in the cytoplasm
   2. Help nascent proteins fold into proper tertiary conformation
   3. Warm up the interior temperature of cells.
   4. Bind to and hydrolyze ATP

Answer 1

Answer 1 -The statement that is not accurate about m RNA splicing is that it is carried by tRNA and its associated proteins. Its the snRNP's and its associated proteins that carry out the splicing  by forming spliceosome complex . snRNP's with other important proteins carry out splicing. U1 , U2, U3 to U6 snRNP,s are major snRNP in splicing.

Answer 2- The major role of chaperone protein is to help and assist nascent protein to fold into proper tertiary confirmation . It plays a key role in binding unfolded proteins and assist them to fold properly to their confirmations so that it can carry out its function. As protein confirmation is important for its function.