What bases are commonly used to deprotonate alpha carbons

Question

Question

Answer 1

Answer #1

The alpha carbon atom in the carbonyl compounds are sp3 hybridised. We need strong bases to deprotonate the hydrogen atoms of alpha carbon atom.

The examples of strong bases uses are as follows

NaOH, or hydroxide bases, NaOEt(Sodium ethoxide) other NaOMe(Sodium methoxide), LDA etc..

Answer 2

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