For Pravastatin , the molecular formula C23H36O7, answer the following a) which is the most acidic...
For Pravastatin , the molecular formula C23H36O7, answer the following
a) which is the most acidic hydrogen(s) in the structure and the most basic position(s) and why
b) Identify all possible stereocenters and determine the maximum number of stereoisomers, determine if any alkenes E or Z
c)Find the IUPAC systematic name and number the carbons to match it to the structure
d)determine how many of the stereocenters are naturally occurring or if it is always a mixture
e)is this molecule optically active why or why not
pictures would also be greatly appreciated
Homework Answers
xAdd Answer to:
For Pravastatin , the
molecular formula C23H36O7, answer the following
a) which is the most
acidic...
For Pravastatin , the molecular formula C23H36O7, answer the following a) all sp or sp2 hybridized...
For Pravastatin , the molecular formula C23H36O7, answer the following a) all sp or sp2 hybridized atoms b)all reasonably stable resonance structures showing lone pairs and charges or if it does not have any resonance structures label the polar bonds using partial positive/partial negative signs c) the most acidic hydrogen(s) in the structure and the most basic position(s) d) Identify all possible stereocenters and determine the maximum number of stereoisomers, determine if any alkenes E or Z pictures would also...
5) (8 pts) Arrange the following compounds from most acidic through neutral to most basic. Briefly...
5) (8 pts) Arrange the following compounds from most acidic through neutral to most basic. Briefly explain your reasoning. 7) (15 pts) a) Write out the 3-step arrow pushing mechanism showing how 1-pentene is hydrated to make 2-pentanol. b) Draw the other 2 alkenes (don't forgel cis/trans isomers!) that could also be hydrated to make 2-pentanol. Briefly explain why 1-pentene is the best choice. II, II,O a) heat Acidic Neutral Basic 6) (18 pts) Consider the Fischer projections of the...
Challenge Problem 5.52 Tartare od OZCCH(OH)CH(OH)COM) was an important compound in the history of stereochemistry, Two...
Challenge Problem 5.52 Tartare od OZCCH(OH)CH(OH)COM) was an important compound in the history of stereochemistry, Two naturally occurring forms of tartaric acid are optically inactive. One optically nactive form has a melting point of 210-212°C, the other has a melting point of 140°C. The inactive tartanic acid with a melting point of 210-212c can be separated into two optically AR +12 active forms of tartanic acid with the same melting point (168-170°c). One optically active tartani adala -12 h and...
N c ?? Gephyrotoxin a) State the molecular formula of gephyrotoxin. b) Give the hybridisation of...
N c ?? Gephyrotoxin a) State the molecular formula of gephyrotoxin. b) Give the hybridisation of carbon atoms a and b in gephyrotoxin. c) Determine the number of double-bond equivalents present in gephyrotoxin, explaining your reasoning State the total number of stereoisomers possible for gephyrotoxin, explaining your reasoning. d) e) Assign the absolute stereochemistry (R or S) of the stereogenic centres labelled c and d in the structure of gephyrotoxin above. 14] A simplified fragment of gephyrotoxin is shown below....
Key concepts: molecular represenations, stereolsomers, RS enantiomeric excess, IPAC naming covention Provide the IUPAC name for...
Key concepts: molecular represenations, stereolsomers, RS enantiomeric excess, IPAC naming covention Provide the IUPAC name for each of the following molecules 0% HJC BM How similar are the names for B and C, even though there is the single change to the structure 2 Rank the priorities of these functional groups and substituents using Cahn-Ingold-Prelog nomenclature. Highest priority will be 1 and lowest will be 5; show your rationale CH:CH:CH CH CHCH:CH CHs,-SCH,-CH: CH:CH:CHCH CHCH, -CH2NHOH,-CH:NO Draw dash/wedge representations for...
5. Which of the following single-stranded DNA sequences is most likely to form a stem-loop structure? a. GACCGTATGC...
5. Which of the following single-stranded DNA sequences is most likely to form a stem-loop structure? a. GACCGTATGCACGGTC b. TCATAGGCGCCGTTCA c. GGATCACGTTACCGCC d. ATAAGATGGGAGCATG The structures below represent the 8 D stereoisomeric aldohexoses. Answer the following (6-7) based on this figure Si carbons ---OH H= =QH --OH H--OH CH,OH HO--- H=CHCH -- - OH CH,OH ---CH HỌC 6 -- - OH Chon D-Glucose HO-- H H -- - OH CH,OH -Marnese -- Hà QH HO--- - OH CHOH Giese HO--...
5. For the following set of Fischer projections answer each of the questions below by circling...
5. For the following set of Fischer projections answer each of the questions below by circling the appropriate letter(s) or letter combination(s). Hint: Redraw the Fischer projections with the longest carbon chain in the vertical direction and having similar atoms in the top and bottom portion. Classify all chiral centers in the first structure as R or S absolute configuration. (X pts) a. Which are optically active? b. Which are meso? c. Which is not an isomer with the others?...
A. Consider the following pairs of structures. Designate each chirality center as (R) or (S) and...
A. Consider the following pairs of structures. Designate each
chirality center as (R) or (S) and identify the
relationship between them by describing them as representing
enantiomers, diastereomers, constitutional isomers, or two
molecules of the same compound. Use handheld molecular models to
check your answers.
B. Tartaric acid
[HO2CCH(OH)CH(OH)CO2H] was an important
compound in the history of stereochemistry. Two naturally occurring
forms of tartaric acid are optically inactive. One optically
inactive form has a melting point of 210 − 212 °...
please answer all parts, thanks! 1. More substituted alkenes are more stable than less substituted alkenes....
please answer all parts, thanks!
1. More substituted alkenes are more stable than less substituted alkenes. Show the orbital overlap that helps to explain this observation. 2. Why is the heat of hydrogenation for an alkene exothermic? Analyze the bonds that are changing. AH = -30 kcal/mol Explain: + H2 3. Treating alkene "A" below with HBr can lead to a number of products. "A" SM + H-Br A bunch of products. For real, hella products. 3.A. Label the stereocenters...
Help on all parts of question 3 would be greatly appreciated! 3. Treating alkene "A" below...
Help on all parts of question 3 would be greatly
appreciated!
3. Treating alkene "A" below with HBr can lead to a number of products. "A" + H-Br A bunch of products. For real, hella products. 3.A. Label the stereocenters in compound "A" as R or S and label the alkene as E or Z. 3.B. Draw the curved arrow mechanism leading to the most stabilized carbo- cation intermediate. (don't do any rearrangements, just acid/base with the alkene) H-Br most...
5) (8 pts) Arrange the following compounds from most acidic through neutral to most basic. Briefly explain your reasoning. 7) (15 pts) a) Write out the 3-step arrow pushing mechanism showing how 1-pentene is hydrated to make 2-pentanol. b) Draw the other 2 alkenes (don't forgel cis/trans isomers!) that could also be hydrated to make 2-pentanol. Briefly explain why 1-pentene is the best choice. II, II,O a) heat Acidic Neutral Basic 6) (18 pts) Consider the Fischer projections of the...
Challenge Problem 5.52 Tartare od OZCCH(OH)CH(OH)COM) was an important compound in the history of stereochemistry, Two naturally occurring forms of tartaric acid are optically inactive. One optically nactive form has a melting point of 210-212°C, the other has a melting point of 140°C. The inactive tartanic acid with a melting point of 210-212c can be separated into two optically AR +12 active forms of tartanic acid with the same melting point (168-170°c). One optically active tartani adala -12 h and...
N c ?? Gephyrotoxin a) State the molecular formula of gephyrotoxin. b) Give the hybridisation of carbon atoms a and b in gephyrotoxin. c) Determine the number of double-bond equivalents present in gephyrotoxin, explaining your reasoning State the total number of stereoisomers possible for gephyrotoxin, explaining your reasoning. d) e) Assign the absolute stereochemistry (R or S) of the stereogenic centres labelled c and d in the structure of gephyrotoxin above. 14] A simplified fragment of gephyrotoxin is shown below....
Key concepts: molecular represenations, stereolsomers, RS enantiomeric excess, IPAC naming covention Provide the IUPAC name for each of the following molecules 0% HJC BM How similar are the names for B and C, even though there is the single change to the structure 2 Rank the priorities of these functional groups and substituents using Cahn-Ingold-Prelog nomenclature. Highest priority will be 1 and lowest will be 5; show your rationale CH:CH:CH CH CHCH:CH CHs,-SCH,-CH: CH:CH:CHCH CHCH, -CH2NHOH,-CH:NO Draw dash/wedge representations for...
5. Which of the following single-stranded DNA sequences is most likely to form a stem-loop structure? a. GACCGTATGCACGGTC b. TCATAGGCGCCGTTCA c. GGATCACGTTACCGCC d. ATAAGATGGGAGCATG The structures below represent the 8 D stereoisomeric aldohexoses. Answer the following (6-7) based on this figure Si carbons ---OH H= =QH --OH H--OH CH,OH HO--- H=CHCH -- - OH CH,OH ---CH HỌC 6 -- - OH Chon D-Glucose HO-- H H -- - OH CH,OH -Marnese -- Hà QH HO--- - OH CHOH Giese HO--...
5. For the following set of Fischer projections answer each of the questions below by circling the appropriate letter(s) or letter combination(s). Hint: Redraw the Fischer projections with the longest carbon chain in the vertical direction and having similar atoms in the top and bottom portion. Classify all chiral centers in the first structure as R or S absolute configuration. (X pts) a. Which are optically active? b. Which are meso? c. Which is not an isomer with the others?...
A. Consider the following pairs of structures. Designate each
chirality center as (R) or (S) and identify the
relationship between them by describing them as representing
enantiomers, diastereomers, constitutional isomers, or two
molecules of the same compound. Use handheld molecular models to
check your answers.
B. Tartaric acid
[HO2CCH(OH)CH(OH)CO2H] was an important
compound in the history of stereochemistry. Two naturally occurring
forms of tartaric acid are optically inactive. One optically
inactive form has a melting point of 210 − 212 °...
please answer all parts, thanks!
1. More substituted alkenes are more stable than less substituted alkenes. Show the orbital overlap that helps to explain this observation. 2. Why is the heat of hydrogenation for an alkene exothermic? Analyze the bonds that are changing. AH = -30 kcal/mol Explain: + H2 3. Treating alkene "A" below with HBr can lead to a number of products. "A" SM + H-Br A bunch of products. For real, hella products. 3.A. Label the stereocenters...
Help on all parts of question 3 would be greatly
appreciated!
3. Treating alkene "A" below with HBr can lead to a number of products. "A" + H-Br A bunch of products. For real, hella products. 3.A. Label the stereocenters in compound "A" as R or S and label the alkene as E or Z. 3.B. Draw the curved arrow mechanism leading to the most stabilized carbo- cation intermediate. (don't do any rearrangements, just acid/base with the alkene) H-Br most...
Most questions answered within 3 hours.
-
Programming project in Java:
You are allowed to use the following methods from the
Java API:...
asked 1 minute from now -
The enthalpy change, ΔH, for a reaction at constant pressure is
defined as:
ΔH = ΔE...
asked 6 minutes ago -
What are the two main reasons for including covariates in ANOVA?
a. 1.) To increase within-group...
asked 6 minutes ago -
There are balls numbered 1, 2, 3, 4, 5, 6, 7 in a box, 2 balls...
asked 1 hour ago -
Based on the mutual fund NAVs below, how many shares will $600
buy you, if you...
asked 1 hour ago -
what effect on total protein concentration would you
expect to see during dehydration? explain your reasoning.
asked 1 hour ago -
You are the operations manager of a firm that uses the
continuous review inventory control system....
asked 4 hours ago -
Cost and fair value data for the trading debt securities of
Wildhorse Company at December 31,...
asked 6 hours ago -
In a population of jaguars, a gene with two alleles encodes the
fur color. Allele B...
asked 7 hours ago -
Two copper wires, one 1.80 times the diameter of the other, have
the same current flowing...
asked 7 hours ago -
9. In 2003 the price of ‘home heating oil’ substantially
increased during the harsh winter. In...
asked 7 hours ago -
Match the key paradoxes of negotiation.
Claiming Value
Sticking by your principles
Sticking with your strategy...
asked 8 hours ago