For Pravastatin , the molecular formula C23H36O7, answer the following a) all sp or sp2 hybridized...
For Pravastatin , the molecular formula C23H36O7, answer the following
a) all sp or sp2 hybridized atoms
b)all reasonably stable resonance structures showing lone pairs and charges or if it does not have any resonance structures label the polar bonds using partial positive/partial negative signs
c) the most acidic hydrogen(s) in the structure and the most basic position(s)
d) Identify all possible stereocenters and determine the maximum number of stereoisomers, determine if any alkenes E or Z
pictures would also be greatly appreciated
Homework Answers
Pravastatin is the 6-alpha-hydroxy acid form of mevastatin. It
is a type of drug.
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For Pravastatin , the molecular formula C23H36O7, answer the
following
a) all sp or sp2 hybridized...
For Pravastatin , the molecular formula C23H36O7, answer the following a) which is the most acidic...
For Pravastatin , the molecular formula C23H36O7, answer the following a) which is the most acidic hydrogen(s) in the structure and the most basic position(s) and why b) Identify all possible stereocenters and determine the maximum number of stereoisomers, determine if any alkenes E or Z c)Find the IUPAC systematic name and number the carbons to match it to the structure d)determine how many of the stereocenters are naturally occurring or if it is always a mixture e)is this molecule...
(SIMVASTATIN) is MY MOLECULE A. give all reasonably stable resonance structure or if molecule doesn't have...
(SIMVASTATIN) is MY MOLECULE A. give all reasonably stable resonance structure or if molecule doesn't have resonance then label polar bonds, lone pair, formal charges B. identify the most acidic hydrogens and most basic positions C. ALL SP or Sp2 hybridized atoms (simvastatin)
According to the solutions, all 3 answers are sp2 hybridized. Please explain why. Is there delocalization...
According to the solutions, all 3 answers are sp2 hybridized.
Please explain why.
Is there delocalization of lone pairs?
Determine the hybridization of the labeled atom in each species. a =0: b. I
organic chemistry A carbonyl group, C=O, and an alkene, C=C, double bonds, are both sp2 hybridized....
organic chemistry
A carbonyl group, C=O, and an alkene, C=C, double bonds, are both sp2 hybridized. However, the chemistry of these two functional groups is very different. This can be explained by which of the following statements? a. The bond angle of the carbonyl is larger than the bond angle of the alkene. b. The electronegative oxygen of the C=O group makes this bond polar. d. There is more steric crowding in the carbonyl than in the alkene. Which, if...
please help in all sections asap!! Identify the reagents for each of the following transformations. Select...
please help in all sections asap!!
Identify the reagents for each of the following transformations. Select all that apply. V -a HC=CNa MCPBA NaOEt H2O2, NaOH NBS, heat Conc. H2S04, heat OBH3-THF OH PCC, CH2Cl2 Conc. H2SO4, heat OBH3-THF HC=CNa MCPBA H2O2, NaOH NBS, heat HCCNa ОМСРВА H2O2, NaOH PCC, CH2Cl2 Conc. H2SO4, heat The following two drawings are resonance structures of one compound. But the following two drawings are not resonance structures Not resonance structures They are, in fact,...
please help in all sections asap! The following two drawings are resonance structures of one compound....
please help in all sections asap!
The following two drawings are resonance structures of one compound. a-o But the following two drawings are not resonance structures Not resonance structures They are, in fact, two different compounds. Choose the correct explanation(s). Select all that apply. Benzene does not have three C-C single bond and three C-C double bonds. In fact, all six C-C bonds of the ring have the same bond order and same length. Benzene have three C- single bond...
PLEASE ANSWER ALL A-G, will give thumbs up!! FOR A, just need explanation why reaction occurs...
PLEASE ANSWER ALL A-G, will
give thumbs up!! FOR A, just need explanation why reaction occurs
at C2 position rather than C3, already have mechanism drawn...
PLEASE EXPLAIN OR AT LEAST
JUST ANSWER ALL ASAP, BEFORE TOMORROW!!
10. Furan, an aromatic heterocycle, is capable of undergoing electrophilic aromatic substitution. When furan is treated with an acid chloride in the presence of a Lewis acid, Friedel-Crafts acylation occurs in which the electrophile is installed exclusively at the C2 position. Provide...
Name the following compounds. Don't forget to specify stercochemistry when appropriate 2. Draw the structures of...
Name the following compounds. Don't forget to specify stercochemistry when appropriate 2. Draw the structures of cis-2-ethylhexa-1,4-diene E-2,4-dimethylhexa-1,4-diene 3. Assign E or Z configuration to the following alkenes. (Circle highest priority groups) Br сн Вr сH,сн,Br NH2CH CH2CHCH CH,OH NH2 CH2CH2Br NEC Which of the following compounds that can exist as a mixture of stereoisomers? Draw each b. 1-chloro-2-methylbut-2-ene 4. a. 1-chloropropene c. 1,1-dichloroethene 5. Calculate the degree of unsaturation for codeine, CisHaiNO,. Show your work. 6. Rank the following...
please solve them clear & be sure thank you . 1. (21 points) Is the following...
please solve them clear & be sure thank you .
1. (21 points) Is the following compound a meso-compound? If yes, show it in 3D in the box below using wedged and dashed bonds to indicate the substituent bond direction and draw the internal mirror plane of symmetry (if any). (3 points) HOOC-CHOH-CHOH-COOH Draw the 3D structures of the stereoisomers of the compound above. Use wedged and dashed bonds to indicate the substituent bond direction in each stereoisomer. [Hint: if...
please help in all sections asap!! Which type of electron is the highest in energy? An electron in an an...
please help in all sections asap!!
Which type of electron is the highest in energy? An electron in an anti-bonding molecular orbital. An electron in a bonding molecular orbital. An electron in an atomic orbital. O A non-bonding electron. Choose a systematic name for the following compound. 1,4 dimethyl ethyl benzene 1,4 diethyl methyl benzene 1,4-diisopropylbenzene 1,4 dipropylbenzene Answer the following questions. -OR Would you expect the above compound to be aromatic? Yes No Choose the correct explanations for the...
According to the solutions, all 3 answers are sp2 hybridized.
Please explain why.
Is there delocalization of lone pairs?
Determine the hybridization of the labeled atom in each species. a =0: b. I
organic chemistry
A carbonyl group, C=O, and an alkene, C=C, double bonds, are both sp2 hybridized. However, the chemistry of these two functional groups is very different. This can be explained by which of the following statements? a. The bond angle of the carbonyl is larger than the bond angle of the alkene. b. The electronegative oxygen of the C=O group makes this bond polar. d. There is more steric crowding in the carbonyl than in the alkene. Which, if...
please help in all sections asap!!
Identify the reagents for each of the following transformations. Select all that apply. V -a HC=CNa MCPBA NaOEt H2O2, NaOH NBS, heat Conc. H2S04, heat OBH3-THF OH PCC, CH2Cl2 Conc. H2SO4, heat OBH3-THF HC=CNa MCPBA H2O2, NaOH NBS, heat HCCNa ОМСРВА H2O2, NaOH PCC, CH2Cl2 Conc. H2SO4, heat The following two drawings are resonance structures of one compound. But the following two drawings are not resonance structures Not resonance structures They are, in fact,...
please help in all sections asap!
The following two drawings are resonance structures of one compound. a-o But the following two drawings are not resonance structures Not resonance structures They are, in fact, two different compounds. Choose the correct explanation(s). Select all that apply. Benzene does not have three C-C single bond and three C-C double bonds. In fact, all six C-C bonds of the ring have the same bond order and same length. Benzene have three C- single bond...
PLEASE ANSWER ALL A-G, will
give thumbs up!! FOR A, just need explanation why reaction occurs
at C2 position rather than C3, already have mechanism drawn...
PLEASE EXPLAIN OR AT LEAST
JUST ANSWER ALL ASAP, BEFORE TOMORROW!!
10. Furan, an aromatic heterocycle, is capable of undergoing electrophilic aromatic substitution. When furan is treated with an acid chloride in the presence of a Lewis acid, Friedel-Crafts acylation occurs in which the electrophile is installed exclusively at the C2 position. Provide...
Name the following compounds. Don't forget to specify stercochemistry when appropriate 2. Draw the structures of cis-2-ethylhexa-1,4-diene E-2,4-dimethylhexa-1,4-diene 3. Assign E or Z configuration to the following alkenes. (Circle highest priority groups) Br сн Вr сH,сн,Br NH2CH CH2CHCH CH,OH NH2 CH2CH2Br NEC Which of the following compounds that can exist as a mixture of stereoisomers? Draw each b. 1-chloro-2-methylbut-2-ene 4. a. 1-chloropropene c. 1,1-dichloroethene 5. Calculate the degree of unsaturation for codeine, CisHaiNO,. Show your work. 6. Rank the following...
please solve them clear & be sure thank you .
1. (21 points) Is the following compound a meso-compound? If yes, show it in 3D in the box below using wedged and dashed bonds to indicate the substituent bond direction and draw the internal mirror plane of symmetry (if any). (3 points) HOOC-CHOH-CHOH-COOH Draw the 3D structures of the stereoisomers of the compound above. Use wedged and dashed bonds to indicate the substituent bond direction in each stereoisomer. [Hint: if...
please help in all sections asap!!
Which type of electron is the highest in energy? An electron in an anti-bonding molecular orbital. An electron in a bonding molecular orbital. An electron in an atomic orbital. O A non-bonding electron. Choose a systematic name for the following compound. 1,4 dimethyl ethyl benzene 1,4 diethyl methyl benzene 1,4-diisopropylbenzene 1,4 dipropylbenzene Answer the following questions. -OR Would you expect the above compound to be aromatic? Yes No Choose the correct explanations for the...
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