Step 4 of our mechanism framework is repair, adapt, or dysfunction. Which of the following best describes Step 4 for ricin?
a. The ribosomal adenine is replaced by specialized repair enzymes.
b. Cells adapt to functioning without protein synthesis.
c. The ribosomal deactivation caused by ricin is irreversible.
d. Cells avoid further damage by undergoing mitosis
Ricin consists of an enzymic polypeptide that catalyzes the N-glycosidic cleavage of a specific adenine residue from 28S ribosomal RNA.The enzymatic activity renders ribosomes containing depurinated 28S RNA incapable of protein synthesis.Cells now dysfunction. Therefore option c is correct.
Option a is wrong because damage caused to adenine is not repaired by any specialized enzymes.Option b is wrong because cells cannot adapt to function without protein synthesis as proteins are extremely important for cellular function.Option d is wrong because cells cannot undergo mitosis as even mitosis requires synthesis of specific proteins which cannot happen when ribosomes are deactivated.
Step 4 of our mechanism framework is repair, adapt, or dysfunction. Which of the following best...
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